Volume 16, Issue 3 (7-2026)                   J Adv Biomed Sci. 2026, 16(3): 0-0 | Back to browse issues page

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Mohammadi M R. On the Superiority of LAMP Over PCR for Tick-Borne Relapsing Fever Surveillance. J Adv Biomed Sci. 2026; 16 (3)
URL: http://jabs.fums.ac.ir/article-1-3228-en.html
On the Superiority of LAMP Over PCR for Tick-Borne Relapsing Fever Surveillance
Mohammad Reza Mohammadi *
Department of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran , mreza_mohammadi@modares.ac.ir
Abstract:   (8 Views)
Houmansadr and Soleimani (2025) have provided valuable field-derived evidence supporting glpQ-LAMP as a pragmatic, economical, and sensitive approach for TBRF monitoring in tick vectors (4). Given that TBRF cases continue to be documented in Iran, with 1,415 cases recorded between 1997 and 2006, especially in the provinces of Ardabil, Hamedan, Zanjan, and Kurdestan, integrating LAMP into regional health laboratories could improve vector surveillance and ultimately reduce diagnostic delays (5). Future studies should therefore focus on validating this technique in clinical specimens obtained from febrile patients living in the same endemic foci, while also incorporating sequencing-based confirmation of discordant samples and systematic assessments of analytical specificity against co-circulating tick-borne pathogens.

 
Keywords: LAMP, PCR, Relapsing fever, Borrelia tholozani, glpQ, Tick-borne disease
     
Type of Study: Letter to the Editor | Subject: Microbiology
Received: 2026/05/11 | Revised: 2026/07/22 | Accepted: 2026/06/23 | Published: 2026/07/1
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