en ميكروبیولوژی Microbiology نامه به سردبیر Letter to the Editor <div style="text-align: justify;"><span style="line-height:115%"><span style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">Houmansadr and Soleimani (2025) have provided valuable field-derived evidence supporting <em>glpQ</em>-LAMP as a pragmatic, economical, and sensitive approach for TBRF monitoring in tick vectors (4). Given that TBRF cases continue to be documented in Iran, with 1,415 cases recorded between 1997 and 2006, especially in the provinces of Ardabil, Hamedan, Zanjan, and Kurdestan, integrating LAMP into regional health laboratories could improve vector surveillance and ultimately reduce diagnostic delays (5). Future studies should therefore focus on validating this technique in clinical specimens obtained from febrile patients living in the same endemic foci, while also incorporating sequencing-based confirmation of discordant samples and systematic assessments of analytical specificity against co-circulating tick-borne pathogens.</span></span></span></span><br> <br> &nbsp;</div> LAMP, PCR, Relapsing fever, Borrelia tholozani, glpQ, Tick-borne disease 0 0 http://jabs.fums.ac.ir/browse.php?a_code=A-10-3483-2&slc_lang=en&sid=1 Mohammad Reza Mohammadi محمدرضا محمدی mreza_mohammadi@modares.ac.ir 100319475328460030815 100319475328460030815 Yes Department of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran گروه باکتری‌شناسی، دانشکده علوم پزشکی، دانشگاه تربیت مدرس، تهران، ایران