Moradi A, Ebrahimipour G, Karkhane M, Marzban A. Surveying the Antioxidant and the Antimicrobial Effects of Aqueous and Ethanolic Extract of Rumex Alveollatus L. on In-vitro Indicator Microorganisms. JABS 2014; 4 (4) :418-426
URL:
http://jabs.fums.ac.ir/article-1-579-en.html
1- Department of Microbiology, Faculty of Biological Sciences, Shahid Beheshti University, Tehran, Iran.
2- Gastroenterology and Liver Diseases Research Center, Shahid Beheshti University of Medical sciences, Tehran, Iran.
3- Department of Microbiology, Faculty of Biological Sciences, Shahid Beheshti University, Tehran, Iran. Biotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. , marzban86@gmail.com
Abstract: (12637 Views)
Background
& Objective: In recent years, more
attention has been devoted to herbal medicines. Up to now, many compounds with
therapeutic effects has been extracted from the herbs. The aim of this study is
to evaluate the antioxidant and the antimicrobial effect of Rumex Alveollatus L. and to partially
identify the effective compounds in this plant.
Materials & Methods: Extraction was performed by using maceration method for
dried flower sample. Then, the antimicrobial effect of aqueous and ethanolic
extracts on eight bacterial sp. and two fungi were tested using disc diffusion
method. The antioxidant effect was also determined
through ferric reducing potency and phosphomolybdenum followed by total phenol
determination. Finally, partial detection of bioactive compounds was conducted
using chemical and calorimetric methods.
Results: The results showed that ethanolic extract had the most
antimicrobial effect while aqueous extract weakly affected bacterial and
fungal strains. Antioxidant experiments also revealed that ethanol extract had
more antioxidant effects than aqueous extract. The most content of total
phenolic compounds was found in ethanol extract. The results of the plant
chemical determination showed the presence of flavonoids, alkaloids,
anthraquinones, tannins, glycosides, and reducing sugars. Conclusion: Considering that few reports
about the therapeutic effect of Rumex alveollatus L. has been published, this
study could be considered as a valuable report about the important role of this
plant on preventing infections and neutralizing oxidant agents.
Type of Study:
Research |
Subject:
Pharmacology Received: 2014/06/8 | Accepted: 2014/08/20 | Published: 2015/02/15
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