fa ساخت و مشخصه یابی نوری نانوذرات گاما آلومینا و بررسی خواص آنتی باکتریال آن نانوتکنولوژی پزشکی Nanomedicine پژوهشي Research <div style="text-align: justify;"><strong><em>Background & Objective:</em> </strong>By increasing resistance due to overuse of antibiotics, it seems necessary to find alternative materials that have both antibacterial properties close to antibiotics and have minimal side effects for humans. Abundant research has been done on the use of nanoparticles with antibacterial properties. The aim of this study is to investigate the antibacterial properties of gamma alumina quantum dots.<br> <strong><em>Materials & Methods:</em></strong> Gamma alumina quantum dots (Al₂O₃<span dir="RTL">-</span>g) were prepared by sol-gel method. Structural, physical and optical properties and of this nanoparticles were appraised by X-ray diffraction (XRD), transmission electron microscopy (TEM), scanning electron microscopy (SEM), photoluminescence spectroscopy (PL), visible-ultraviolet spectroscopy (UV-Vis) and Fourier transform infrared (FTIR) spectroscopy. Biological activity of gamma alumina nanoparticles against 11 types of bacteria was measured by MIC and MBC methods<span dir="RTL">.</span><br> <strong><em>Results:</em></strong> Results show the size of the synthesized nanoparticles is less than ten nanometers. The power of minimal bactericidal concentration (MBC) and minimal inhibitory concentration (MIC) by gamma alumina quantum dots is related to its particle size, which interpenetrates and destroys the bacterial wall more easily. Gamma alumina quantum dots show good activity against bacterial growth.<br> <strong><em>Conclusion:</em></strong> The antibacterial activity of alumina quantum nanoparticles showed desirable effects for a variety of gram-positive and gram-negative bacteria, fungi and yeasts at the lowest inhibitory concentrations. These nanoparticles can be a great alternative to antibiotics and making these nanoparticles is economical, cost-effective and is less time-consuming.<br> &nbsp;</div> Nanoparticles, Quantum dots, γ-Alumina, Sol-Gel, Antibacterial 2986 2995 http://jabs.fums.ac.ir/browse.php?a_code=A-10-2901-1&slc_lang=fa&sid=1 Merat karimi مرآت کریمی merat.karimi123@gmail.com 100319475328460024788 100319475328460024788 No Institute of Nanoscience and Nanotechnology, University of Kashan, Kashan, Iran پژوهشکده علوم فناوری نانو، دانشگاه کاشان، کاشان، ایران Ehsan Sadeghi احسان صادقی sdgh@kashanu.ac.ir 5419823241 100319475328460024789 Yes Institute of Nanoscience and Nanotechnology, University of Kashan, Kashan, Iran پژوهشکده علوم فناوری نانو، دانشگاه کاشان، کاشان، ایران Mostafa Zahedifar مصطفی زاهدی فر zhdfr@kashanu.ac.ir 100319475328460024790 100319475328460024790 No Institute of Nanoscience and Nanotechnology, University of Kashan, Kashan, Iran پژوهشکده علوم فناوری نانو، دانشگاه کاشان، کاشان، ایران