TY - JOUR T1 - Antibacterial Effect of CrO and CoFe2O4 Nanoparticles upon Staphylococcus aureus TT - بررسی اثر ضد باکتریایی نانوذرات CrO و CoFe2O4 روی باکتری استافیلوکوکوس اورئوس JF - JABS JO - JABS VL - 1 IS - 3 UR - http://jabs.fums.ac.ir/article-1-83-en.html Y1 - 2011 SP - 175 EP - 181 KW - Metal nanoparticles of CrO and CoFe2O4 KW - Bactericidal KW - Staphylococcus aureus N2 - Background & Objectives: The use of metal oxide nanoparticles can be effective to eliminate the bacterial infections, as an alternative to antibiotics. In this study, antibacterial properties of nonmaterials of CrO and CoFe2O4 are investigated against Staphylococcus aureus as a major and prevalent pathogenic bacterium to achieve sterile nano-containers. Materials & Methods: Different concentrations of CrO and CoFe2O4 nanoparticles, (0.2, 0.4, 0.6, 0.8, and 1%) of each, were examined with respect to their optical density (OD) culture separately. Different percentages of each nanoparticles were also examined together for the best antibacterial combination. Kinetics of Bactericidal of nanoparticles were calculated in two-hour periods and were compared with the power of other common antibiotics. Ratios of MIC/MBC were calculated by Micro dilution method, to demonstrate the bactericidal power of nanoparticles. Results: The best concentration of the nanoparticles with the highest effect of bactericidal was obtained in the presence of 1% concentration of CrO that the OD of S. aureus culture medium had reduced 4/6 times than the control group (p M3 ER -