en بيوشيمي بالینی Biochemistry پژوهشي Research <div style="text-align: justify;"><span style="font-size:11pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:#2f5496">Background & Objectives:</span></span></span></b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black"> Dyslipidemia is a major public health issue worldwide characterized by changes in lipid index such as cholesterol, Low Density Lipoprotein (LDL), High Density Lipoprotein (HDL) and triglycerides (TG).This manuscript aimed to investigate the associated factors of dyslipidemia in Fasa Persian cohort study.</span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:#2f5496">Materials & Methods:</span></span></span></b> <span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">This cross-sectional study was conducted on the baseline data of Fasa Persian cohort with an initial sample size of 10129 subjects (35-70 years old) in 2021 in Iran. Univariate and multivariate logistic regression models were used to assess the relationship between covariates and dyslipidemia. </span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:#2f5496">Results:</span></span></span></b> <span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">The number of males in this study was 4572 and the number of females was 5557. The prevalence of dyslipidemia in them was 40.8% and 27.7%, respectively (p-value < 0.001), and the prevalence of dyslipidemia in the whole study population was 3407 (33.6%).&nbsp; Dyslipidemia was also more common in alcoholics, opium users, smokers, high glycemic index and higher body mass index (BMI). Men were 1.68 times more likely to have dyslipidemia than women. Opium and cigarette smokers were 1.15 and 1.36 times more likely to have dyslipidemia than non-smokers, respectively. Also, as BMI increases, the likelihood of dyslipidemia becomes higher than the reference group (below 18.5), and people with a BMI greater than 30 have the highest obesity range.</span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:#2f5496">Conclusions:</span></span></span></b> <span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">This study showed that the prevalence of dyslipidemia in the studied population was higher in men than in women and several risk factors such as gender differences, body mass index, smoking and opium use are effective in the prevalence of dyslipidemia.</span></span></span><b><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:#2f5496"></span></span></span></b></span></span></span></span><br> &nbsp;</div> Dyslipidemia , Cholesterol, High Density Lipoprotein, Related Factors 36 46 http://jabs.fums.ac.ir/browse.php?a_code=A-10-123-2&slc_lang=en&sid=1 Abolfazl Karimivaselabadi ابوالفضل کریمی واصل آبادی afz.karimi@gmail.com 100319475328460028496 100319475328460028496 No Department of Clinical Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran گروه بیوشیمی بالینی، دانشکده پزشکی، دانشگاه علوم پزشکی شیراز، شیراز، ایران Shahnaz Karimi شهناز کریمی shahkar20022002@yahoo.com 100319475328460028497 100319475328460028497 No Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran مرکز تحقیقات بیماری‌های غیرواگیر، دانشگاه علوم پزشکی فسا، فسا، ایران Mostafa Bijani مصطفی بیژنی Bizhani_mostafa@yahoo.com 100319475328460028498 100319475328460028498 No Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran مرکز تحقیقات بیماری‌های غیرواگیر، دانشگاه علوم پزشکی فسا، فسا، ایران Abdolmajid Ghasemian majidghasemian86@gmail.com 100319475328460028499 100319475328460028499 No Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran مرکز تحقیقات بیماری‌های غیرواگیر، دانشگاه علوم پزشکی فسا، فسا، ایران Mohammad-Rafi Bazrafshan محمد رفیع بذرافشان Bazrafshan-200@yahoo.com 6 100319475328460028500 No Department of Nursing, School of Nursing, Larestan University of Medical Sciences, Larestan, Iran گروه پرستاری، دانشکده پرستاری، دانشگاه علوم پزشکی لارستان، لارستان، ایران Silvia Barbaresi سیلویا باربارسی 100319475328460028501 100319475328460028501 No Department of Movement and Sports Sciences, Ghent University, Ghent, Belgium گروه حرکت و علوم ورزشی، دانشگاه گنت، گنت، بلژیک Mehdi Sharafi مهدی شرفی mehdisharafi_2002@yahoo.com 100319475328460028502 100319475328460028502 No Social Determinants in Health Promotion Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran مرکز تحقیقات عوامل اجتماعی در ارتقای سلامت، موسسه بهداشت هرمزگان، دانشگاه علوم پزشکی هرمزگان، بندرعباس، ایران Azizallah Dehghan عزیزاله دهقان dehghanaz@gmail.com 100319475328460028503 100319475328460028503 Yes Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran مرکز تحقیقات بیماری‌های غیرواگیر، دانشگاه علوم پزشکی فسا، فسا، ایران