@article{ author = {Sohrabi, Noushin and Tebyanyan, Majid and Mahdavi, Mehdi}, title = {Evaluation of Th1 and TH2 Cytokine Network in Aspergilus Infected Tumor Bearing Mice}, abstract ={Background & Objective: Invasive Aspergillosis is a fatal infection in immunocompromised patients. The aim of this study was to evaluate the interaction of infectious with Aspergillus and tumor on immune response and cytokine network in Aspergillus infected tumor-bearing mice. Materials and Methods: Mice were implanted by sterile pieces of mouse mammary tumor and then infected by Aspergillus conidia by IV injection. Control groups mice were infected with Aspergillus conidia and/or implanted by sterile funga pieces of mouse mammary tumor. Seven days after Aspergillus infection, cytokine production of extracted splenocytes was analyzed by ELISA method. Results: Tumor bearing mice which were infected with Aspergillus conidia showed remarkable increase in IL-4 production. Conversely, the levels of IFN-γ and IL-10 were decreased and TNF-α was increased moderately. Conclution: Probably, Aspergillus infection could change cytokine production from CD4+ T helper cells and acquired immunity of tumor bearing mice. This point may be considered for better management of Aspergillus-infected patients suffering from cancer.}, Keywords = {Aspergillosis, Tumor bearing mice, Th1, Th2, Cytokines}, volume = {2}, Number = {1}, pages = {1-5}, publisher = {Fasa University of Medical Sciences}, url = {http://jabs.fums.ac.ir/article-1-66-en.html}, eprint = {http://jabs.fums.ac.ir/article-1-66-en.pdf}, journal = {Journal of Advanced Biomedical Sciences}, issn = {}, eissn = {2783-1523}, year = {2012} } @article{ author = {HemayatkhahJahromi, Vahid and KarimiJashni, Hojatallah and Mosallanezhad, Mozhdeh and Mosallanezhad, Monireh and Jamali, Hooshangh and Izadpanah, Peym}, title = {The Effect of Microwave Ovens Radiation Leakage on Testis Tissue and Sex Hormones in Immature Mice}, abstract ={Background & Objective: The vast use of microwave ovens in today's modern life and possible exposure of users to radiation exited from the oven lead us to investigate the effect of this radiation on sex hormones. In the present study, the effect of microwave ovens radiation leakage on concentration of LH, FSH and testosterone hormones has been investigated. Materials & Methods: Thirteen immature two weeks- old male mice which weighing about 10 grams were used in this experimental study. Animals were randomly divided into 3 groups. Each group contained 10 mice. Experimental group 1 and 2 were exposed to microwave oven 30 and 90 minutes daily for 30 days, respectively. The control group received no radiation. Animals were anaesthetized and serum samples were stored. The concentration of testosterone, FSH and LH hormones were measured by RAI method. Results: The serum testosterone levels showed significant decrease in experimental group 2. But levels of LH and FSH indicate no significant different in experimental group 1 and 2 when compared to control group. Conclusion: Our results suggest that radiation leakage of microwave ovens might causes dysfunction in the levels of testosterone hormone secretion.}, Keywords = {Microwave Oven, Testosterone, FSH, LH, Mice}, volume = {2}, Number = {1}, pages = {6-11}, publisher = {Fasa University of Medical Sciences}, url = {http://jabs.fums.ac.ir/article-1-67-en.html}, eprint = {http://jabs.fums.ac.ir/article-1-67-en.pdf}, journal = {Journal of Advanced Biomedical Sciences}, issn = {}, eissn = {2783-1523}, year = {2012} } @article{ author = {Faramarzi, Tehereh and JonidiJafari, Ahmad and Dehghani, Somayyeh and Mirzabeygi, Maryam and Naseh, Monireh and RahbarArasteh, Homeir}, title = {A survey on Bacterial Contamination of Food Supply in the West of Tehran}, abstract ={Background & Objective: Transfer of food born diseases is a common problem in hygiene and public health. The bacteria are the most important factors of food contamination and intoxications. The aim of this study is to determine the bacterial contamination of food supply in the west of Tehran supermarkets. Materials & Methods: In this descriptive cross-sectional study, 642 samples of foods were taken randomly from west of Tehran supermarkets. The levels of bacterial contamination of the foods were assessed in the department of food and drug microbiology of lab, affiliated to Iran University of medical science. Results: Salads were the most (50%) and protein products (6.36%) the least rate in terms of mesophilic bacteria contamination. Also, sweets (13.46%) and protein products (1.73%) in terms of Coliforms. Salads (58.33%) and dairy products (9.84%) with respect to Escherichia coli, sweets (4.81%) and salads (0%) in terms of Staphylococcus aureus, sweets (4.81%) and dairy products (0.39%) with respect to Bacillus cereus, were the most and least contaminated foods, respectively. Conclusion: In overall, salads had the most contamination percentage with respect to mesophilic bacteria, Escherichia coli and Enterococcus (P . According to our study, we conclude that training of dealers and food suppliers are necessary and healthy principals should be followed. Also supervision on food packing and storage should be considered to prevent food microbial contamination.}, Keywords = {Foods, Bacterial contamination, West of Tehran}, volume = {2}, Number = {1}, pages = {11-18}, publisher = {Fasa University of Medical Sciences}, url = {http://jabs.fums.ac.ir/article-1-68-en.html}, eprint = {http://jabs.fums.ac.ir/article-1-68-en.pdf}, journal = {Journal of Advanced Biomedical Sciences}, issn = {}, eissn = {2783-1523}, year = {2012} } @article{ author = {Baghbani-arani, Fahimeh and Tajbakhsh, Mercedeh and HashemiSoltaniyeh, Atiyeh and Rajaei, Bahareh and Siadat, Seyed Davar and Aghasadeghi, Mohamahreza and Sadat, Seyed Mehdi}, title = {Molecular Typing of Salmonella paratyphi B and Salmonella paratyphi C Isolates from Clinical Samples in Iran}, abstract ={Background & Objective: Molecular typing is an important tool in surveillance and outbreak investigations of human Salmonella infections. In this study, Subtyping of Salmonella Paratyphi B and C isolates derived from Iranian patients was carried out by RAPD-PCR to assess the extent of genetic diversity of these isolates. Materials & Methods: Fourteen Salmonella isolates including 6 strains of Salmonella paratyphi B and 8 strains of Salmonella paratyphi C were characterized using RAPD-PCR. Two arbitrary primers, namely OPP-16 and P1254 were used for RAPD analysis and the dendrograms were constructed with NTsys 2.0 computer software. Results: Both primers showed high discriminatory power in differentiating of the related strains of Salmonella. The dendrograms constructed based on RAPD-PCR profiles (with both primers) involving 14 salmonella strains revealed 4 distinct patterns, indicating that these isolates are genetically heterogeneous. Furthermore, a good correlation was not observed between the serotype and the molecular profiles obtained from RAPD data of the Salmonella isolates. Conclusion: The findings of the present study verify the usefulness of RAPD-PCR in characterizing and comparing strains of Salmonella Paratyphi B and C.}, Keywords = {Salmonella, RAPD-PCR, NTsys, Genetic Diversity}, volume = {2}, Number = {1}, pages = {19-25}, publisher = {Fasa University of Medical Sciences}, url = {http://jabs.fums.ac.ir/article-1-72-en.html}, eprint = {http://jabs.fums.ac.ir/article-1-72-en.pdf}, journal = {Journal of Advanced Biomedical Sciences}, issn = {}, eissn = {2783-1523}, year = {2012} } @article{ author = {KhaniJeihooni, Ali and Hatami, Mahmood and Kashfi, Seyed Mansour and Heshmati, Hashem}, title = {The Effectiveness of Education Based on BASNEF Model Program in Promotion of Preventive Behavior of Leishmaniasis among Health Workers and Families under Health Centers Coverage}, abstract ={Background & Objective: Intervention of educational training in order to prevent the leishmaniasis in endemic areas seems necessary. This study was implemented with the aim of assessing the effectiveness of education based on BASNEF Model program in promotion of preventive behavior of leishmaniasis among Health workers and families under the coverage of Health centers. Materials & Methods: An intervention study was carried out in rural health centers during 2009. Questionnaires were completed by 20 health- workers of two rural health centers. Also 20 families under the coverage of this health centers were randomly selected to complete the questionnaire. Then four training sessions for health workers and 2 training sessions for the influential individuals were conducted to increase the enabling factors and solving their problems, weekly meetings was held with health workers representatives. After three months of health workers training the data were collected again and analyzed via Chi- Square, T Independent, T pair, Regression and Mann- Whitney statistics. Results: The mean score for to knowledge, attitude, behavior intension, enabling factors and health workers behaviors significantly increased after educational intervention in experimental group and influential individuals. The mean scores for knowledge, attitude, behavior intension, enabling factors and the behavior of attendant families under coverage also increased significantly. Conclusion: Educational program of BASNEF Model, leads to behavior change of health workers and eventually their training behavior leads to preventive actions in families under coverage.}, Keywords = {Health Workers, Coetaneous Leishmaniasis, BASNEF Model, Health Education}, volume = {2}, Number = {1}, pages = {26-33}, publisher = {Fasa University of Medical Sciences}, url = {http://jabs.fums.ac.ir/article-1-70-en.html}, eprint = {http://jabs.fums.ac.ir/article-1-70-en.pdf}, journal = {Journal of Advanced Biomedical Sciences}, issn = {}, eissn = {2783-1523}, year = {2012} } @article{ author = {Namdar, Azam and Bigizadeh, Shiva and Naghizadeh, Mohammad Mehdi}, title = {Measuring Health Belief Model components in adopting preventive behaviors of cervical cancer}, abstract ={Background & Objective: Cervical cancer is the second prevalent women cancer in the world. This cancer is found preventable because of having the prolong time before the appearance, its complications and the available proper screening program and possibility of the primary lesion treatment. Since the Health Belief Model is one of the applicable praxeology model in health education to prevent and control of diseases. Therefore, this study was aimed to determine the Health Belief Model components in adopting preventive behaviors in cervical cancer in women. Materials & Methods: This descriptive-analytical study was carried out on 213 married 20-65 year-old women selected by a two-stage sampling method. The data was collected by a valid and reliable questionnaire and interview. This questionnaire based on health belief model correlation (components Perceived Susceptibility and Severity, Perceived Barriers and Benefits, Self-efficacy) with behavior survey. The data were analyzed by using descriptive statistics and Mann-Whhitney test, Kruskal-wallis test, and Regression by SPSS software. Results: The mean age of the study group was 40.6 ± 12.1. The results show that 32.5% of them had at least one time examined for Pap smear test out of which only 7.9% of them had this test on a regular interval. Only 12% of them had an adequate knowledge about the cervical cancer and its preventive measure. 90% of them had inappropriate behavior. The average score of knowledge was 6.73± 2.97 which considered as moderate. Regression analysis showed the knowledge (P=0.009), job (P=0.005), perceived barriers (P<0.001) and perceived severity (P=0.036) determine as predictors in the final behavior. Conclusion: Perceived barriers and knowledge behind the strongest predictor of behavior. Educational programs are recommended based on the health belief model with emphasis on reducing barriers and increasing awareness to improve behavior.}, Keywords = {Cervical cancer , Health Belief Model, Papanicolaou Smear, knowledge}, volume = {2}, Number = {1}, pages = {34-44}, publisher = {Fasa University of Medical Sciences}, url = {http://jabs.fums.ac.ir/article-1-71-en.html}, eprint = {http://jabs.fums.ac.ir/article-1-71-en.pdf}, journal = {Journal of Advanced Biomedical Sciences}, issn = {}, eissn = {2783-1523}, year = {2012} } @article{ author = {Behzadpour, Mahin and Khanjani, Narges}, title = {The Prevalence of Different Human Immunodeficiency Virus Transmission Routes and Knowledge about AIDS in Infected People with HIV in Sirjan}, abstract ={Background & Objective: The immune system of Patients with Acquired Immune Deficiency Syndrome (AIDS) is weekend because of Human immunodeficiency virus (HIV) infection, and they become vulnerable to several opportunistic and non-opportunistic pathogens and different carcinomas. IV drug abuse, sexual contact, occupational transmission, blood transfusion and maternal-fetal transmission are well known transmission routes for HIV infection. This study was under taken to investigate the prevalence of HIV transmission routs in the HIV infected population of Sirjan, and their knowledge about the disease, in order to plan better preventive strategies. Materials & Methods: A cross sectional study was planned. During a 6-month period in 2010, all of the HIV infected people in Sirjan (old and new cases) who had a file at the consultation center for high risk behavior, completed a valid and reliable questionnaire. Results: The definite route of transmission was not clear in any of the patients because they had more than one suspicious route. Injected drug abusers were the most common (88.4%) followed by those who got tattoos (79.1%), invasive therapeutic procedures, dentistry, surgery and endoscopy (56.1%), high risk sexual behavior (62.8%), bloodletting (9.3%), injuries in the barbershop (9.3%) and blood transfusion (2.3%). Conclusion: All of the HIV infected cases in Sirjan were involved with several high risk behaviors, but the major route of transmission, similar to other parts of the country was injected drug abuse. Educational programs for prevention of AIDS should be followed seriously and special attention should be paid to groups with multiple high risk behaviors.}, Keywords = {AIDS, Sirjan, Knowledge, Transmission routes}, volume = {2}, Number = {1}, pages = {45-52}, publisher = {Fasa University of Medical Sciences}, url = {http://jabs.fums.ac.ir/article-1-69-en.html}, eprint = {http://jabs.fums.ac.ir/article-1-69-en.pdf}, journal = {Journal of Advanced Biomedical Sciences}, issn = {}, eissn = {2783-1523}, year = {2012} } @article{ author = {Zahmatkeshan, Nasrin and bagherzadeh, razieh and Akaberian, Sherafat and yazdankhah, Mohammad Reza and Mirzaei, kamran and Yazdanpanah, Siyamak and Khoramroodi, Rozita and Gharibi, Tayebe and kamali, Farahnaz and Jamand, Tayebe}, title = {Assessing Quality Of Life and related factors in Bushehr,s elders – 1387-8}, abstract ={ Background & Objective : Added to human life and achievements of the 21st century is one of the elderly population. Age increase is not disease it is a normal change that affect everybody. Elders should be support due to aging, decrease their abilities and high risk conditions. Their needs will be asses and evaluate in physical, social and spiritual aspects .Therefore this study was done for assess quality of life and related factors in elders population in Bushehr. Methods & Materials: This is descript - analytic study that was done on 360 elders in Bushehr. Method of sampling was cluster random sampling. In this study use of two questionnaires include demographic data questionnaire and SF-36 questionnaire for assess QOL. Data collected through client interview. Data were collected, recoding and analysis by SPSS 13 and descript - analytical statistic tests. Results: Results showed that mean scores of physical and mental health of Bushehr,s elders is below 50. So, results showed that physical and mental health aspects of quality of life have significant statistical correlation with economic status (p<0.001), employment (p<0.001), chronic illness (p<0.001), educational level (p<0,001), insurance service (p<0.001) and owner house (p<0.001) and no significant interrelation with sex, activity daily living and life condition. No significant interrelation between men and women in quality of life aspects. Conclusion: According to mean score of QOL in this study was 0-100, results showed that mean score of Bushehr,s elders population is below 50, and this is need to pay attention . Therefore, managers should be considered suitable plan for better quality of life in elderly.}, Keywords = { Elder, physical health, mental health, Quality of life}, volume = {2}, Number = {1}, pages = {53-58}, publisher = {Fasa University of Medical Sciences}, url = {http://jabs.fums.ac.ir/article-1-65-en.html}, eprint = {http://jabs.fums.ac.ir/article-1-65-en.pdf}, journal = {Journal of Advanced Biomedical Sciences}, issn = {}, eissn = {2783-1523}, year = {2012} }