@article{ 
author = {GhorbaniParsa, Fatemeh and HosseinPourFeizi, Mohammad Ali},  
title = {An Overview of the Second and Third-Generation of DNA Sequencing Technologies}, 
abstract ={DNA sequence determination is a tremendous human achievement. DNA sequencing includes several methods and technologies in use for determining the order of the nucleotide bases in a molecule of nucleic acid. Knowledge of DNA sequences has become indispensable for the basic biological researches. Nucleotides sequence determination is used in numerous applied fields such as diagnostics, biotechnology, forensic biology and biological systematics. The advent of DNA sequencing has significantly accelerated biological researches and discoveries. There are several generations of DNA sequencing technologies that can be well characterized through their nature and the kind of output they provide. Dideoxy terminator sequencing developed by Sanger dominated for 30 years and was the workhorse used for the Human Genome Project. In 2005 the first 2nd generation sequencer was presented with an output orders of magnitude higher than Sanger sequencing and dramatically decreased cost. We are now at the dawn of the 3rd generation of sequencing systems. Researchers in the field of genetics in Iran use this technology in their studies, but unfortunately our literature lacks proper Persian language resources. This review briefly describes the current high-throughput nucleotide sequencing platforms commercially available.},  
Keywords = {DNA sequencing, High Throughput Nucleotide Sequencing, second generation sequencing, third generation sequencing},
volume = {7},
Number = {4}, 
pages = {428-437}, 
publisher = {Fasa University of Medical Sciences},
url = {http://jabs.fums.ac.ir/article-1-1262-en.html},  
eprint = {http://jabs.fums.ac.ir/article-1-1262-en.pdf},  
journal = {Journal of Advanced Biomedical Sciences},  
issn = {}, 
eissn = {2783-1523}, 
year = {2017}  
}

@article{ 
author = {Ahrarifar, Mansoureh and BaseriSalehi, Maji},  
title = {Determining the relationship between cagA+ Helicobacter Pylori infection and microalbuminuria in type2 diabetic rats}, 
abstract ={Background & Objectives: Microalbuminuria is a metabolic disease, which is related to the development of diabetic nephropathy. There are several reports indicating high frequency of the occurrence of Helicobacter pylori infection in diabetic patients. It means that probably, there is a relationship between cagA positive Helicobacter pylori and microalbuminuria in diabetic patients. Hence, the present study was conducted to investigate the relationship between cagA positive Helicobacter pylori infection and microalbuminuria in the patients with type 2 diabetes. Material & Methods: Totally, 76 blood and urine samples were collected from patients with type 2 diabetes. The blood samples were used to assess Glycoside Hemoglobin, Fasting Blood Sugar, two-hour postprandial Glucose, Anti-HpIgG and Anti-HpIgM. Molecular method was carried out for identification and helicobacter pylori positive samples were tested for the detection of cagA gene. Finally, Chi-Square test and Fisher technique were applied to analyze the data. Results: The results obtained from this study indicated that Helicobacter pylori was isolated from 28 patients (36.84%) from which, 21 patients (75%) were afflicted with microalbuminuria and 8 samples (25%) were cagA genes positive. The results indicated that there was no statistically significant difference between cagA gene of Helicobacter pylori and microalbuminuria in patients with type 2 diabetes. Conclusion: the findings showed that there was no significant correlation between cagA gene positive Helicobacter pylori infection, and microalbuminuria in the patients with type 2 diabetes.  },  
Keywords = {Helicobacterpylori, cagA gene,microalbuminuria},
volume = {7},
Number = {4}, 
pages = {438-446}, 
publisher = {Fasa University of Medical Sciences},
url = {http://jabs.fums.ac.ir/article-1-1160-en.html},  
eprint = {http://jabs.fums.ac.ir/article-1-1160-en.pdf},  
journal = {Journal of Advanced Biomedical Sciences},  
issn = {}, 
eissn = {2783-1523}, 
year = {2017}  
}

@article{ 
author = {Sistani, Sajad and Raeeszadeh, Mahdieh and Amiri, Aliakbar},  
title = {The phytoestrogenic effect of hydroalcoholic extract of alfalfa on oxidative stress and follicle formation in adult female Wistar rats}, 
abstract ={Background & Objectives: Today, Infertility problems including lack of follicle formation, among other things, are of paramount importance. The aim of this study was to investigate the effect of hydroalcoholic extract of alfalfa on oxidative stress and ovarian tissue in female rats. Materials & Methods: In this experimental-interventional study, 24 rats weighing 200-250g were randomly divided into three groups: control (no treatment) and experimental groups (T1 and T2) which received alfalfa extract at 25 and 50mg/kg intraperitoneally for 25 days, respectively. Body weight of animals and their ovarian weight were measured. The left ovary was prepared for histological study. The antioxidant capacity in serum and malondialdehyde in right ovary extracts were also measured. Results: At the end of the study, the body weight of the animals in both control and experimental groups compared to that of pre-intervention time, but the increase was not statistically significant (P>0.05). The most ovarian weight was observed in T2group (160g) and the lowest weight was in the control group (146g). The primary and secondary follicles and corpus luteum were the highest number in the T2group of alfalfa extract and the lowest number in the control group. The serum antioxidant capacity in T1 and T2groups were about 922 and 937µmol/ml, respectively, and the lowest amount was in the control group with 780µmol/ml and the difference was significant. Malondialdehyde concentration in control and T2gruop were the average of 0.35 and 0.22µmol/ml, respectively (P<0.05). Conclusion: Hydroalcoholic extract of alfalfa with phytoestrogenic and oxidative stress control effects can enhance ovarian activity in adult rats.  },  
Keywords = {Hydroalcoholic extract of alfalfa, ovary, oxidative stress, Wistar rat},
volume = {7},
Number = {4}, 
pages = {447-454}, 
publisher = {Fasa University of Medical Sciences},
url = {http://jabs.fums.ac.ir/article-1-1209-en.html},  
eprint = {http://jabs.fums.ac.ir/article-1-1209-en.pdf},  
journal = {Journal of Advanced Biomedical Sciences},  
issn = {}, 
eissn = {2783-1523}, 
year = {2017}  
}

@article{ 
author = {Bamdad, Kourosh and Mohammadgani, Bagher and Dadfar, Fereshteh and Moradi, Ali},  
title = {The effect of gold, silver and zinc oxide nanoparticles on oxidative stress parameters level in the liver, heart and lung of male mice}, 
abstract ={Background & Objective: Nowadays, the beneficial effects of nanomaterials are accepted in medicine and industry. Considering the increasing use of nanoparticles and their possible toxicity, the effect of nanoparticles on oxidative stress markers was investigated in this study. Material & Methods: In this experimental- interventional study, 32 Balb mice were divided into 4 groups of 8. The control group received saline, and other three groups received gold, silver, and zinc oxide nanoparticles at a concentration of 100 PPM with IP injection during 28 days. After anesthesia, the tissues of liver, heart and lung were removed, and the activity level of oxidative stress markers was evaluated. Results: MDA level was significantly increased in zinc oxide treatment group in all three tissues and in gold treatment group in liver tissue. This factor showed a significant decrease in silver nanoparticle treatment in these tissues. The activity of catalase and glutathione peroxidase enzymes in the treatment of silver nanoparticle showed a significant increase. While in the treatment group with zinc oxide and gold nanoparticles, the activity of these enzymes decreased, this decrease was significant only in zinc oxide nanoparticle. Conclusion: It is concluded that the silver nanoparticle acts as a useful nanoparticle by decreasing MDA and oxidative stress and inducing antioxidant enzymes, while the effect of zinc oxide nanoparticle shows its toxicity.  },  
Keywords = { Oxidative stress, Nanoparticles, Silver, Gold, Zinc oxide  },
volume = {7},
Number = {4}, 
pages = {455-464}, 
publisher = {Fasa University of Medical Sciences},
url = {http://jabs.fums.ac.ir/article-1-1176-en.html},  
eprint = {http://jabs.fums.ac.ir/article-1-1176-en.pdf},  
journal = {Journal of Advanced Biomedical Sciences},  
issn = {}, 
eissn = {2783-1523}, 
year = {2017}  
}

@article{ 
author = {AzizianShermeh, Omid and Taherizadeh, Mojgan and Valizadeh, Moharam and Qasemi, Ali},  
title = {robial and Antioxidant Activities and Determining Phenolic and Flavonoid Contents of the Extracts of Five Species from Different Families of the Medicinal Plants Grown in Sistan and Baluchestan Province}, 
abstract ={Background & Objectives: Traditionally use of the medicinal plants for treating of diseases. This present study is carried out to evaluate the antimicrobial and antioxidant activities and determination of total phenolic and flavonoid contents of three extracts (Methanolic, Ethanolic and Aqueous) of five different species of medicinal plants such as Withania somnifera L. Dunal., Salvia rhytidea Bent, Levisticum officinale L, Seidlitzia rosmarinus L., and Achillea wilhelmsii L. Material & Methods: After preparing the extracts with maceration method, antioxidant activities were determined by two methods (DPPH and FRAP) and antimicrobial activities were estimated by Disk-Diffusion method against bacteria (Staphylococcus aureus, Bacillus cereus, Escherichia coli and fungi (Aspergillus niger and Candida albicans) and phenolic and flavonoid contents were determined by Folin-Ciocaltiu, Aluminum Chloride colorimetric. Results: The results showed that, the methanolic extract of W. somnifera had maximum total phenolic (41.45±4.64 mgGAE/gExtract) and flavonoid contents (35.21±2.54 mgQUE/gExtract) and antioxidant activity, (IC50=8.12±1.36µg/ml, 58.19±1.68 mM Fe2+/mgExtract) and antimicrobial activity against Staphylococcus aureus and Candida albicans with the diameter of inhibition zone (29±1.06 and (27±1.00 mm) respectively. In contrast, the aqueous extract of L. officinale had minimum value of total phenolic (17.12±1.93 mgGAE/gExtract) and flavonoid contents (12.61±2.06 mgQUE/gExtract) and antioxidant activity (IC50=121.43±3.36µg/ml, 13.74±2.52 mM Fe2+/mgExtract) and antimicrobial activity against Bacillus cereus and Aspergillus niger with the diameter of inhibition zone (4±0.57 and 5±1.00 mm) respectively. Conclusion: Overall, based on the results, the studied plants can be a good candidate for the treatment of diseases caused by oxidative stress, and diseases are caused by pathogenic microbes.    },  
Keywords = {Antimicrobial activity, Antioxidant activity, Phenolic content, Flavonoid content, Sistan and Baluchestan province},
volume = {7},
Number = {4}, 
pages = {465-479}, 
publisher = {Fasa University of Medical Sciences},
url = {http://jabs.fums.ac.ir/article-1-1387-en.html},  
eprint = {http://jabs.fums.ac.ir/article-1-1387-en.pdf},  
journal = {Journal of Advanced Biomedical Sciences},  
issn = {}, 
eissn = {2783-1523}, 
year = {2017}  
}

@article{ 
author = {Azizvakili, Fatemeh and Saadatnia, Gita and Hadizade, Mahnaz},  
title = {Investigating the relationship between Human Papillomavirus and Herpes Simplex Virus Type 1 and 2 with Endometriosis Lesions}, 
abstract ={Background & Objective: Endometriosis is one of the most common diseases in women, in which endometrial tissue begins to grow outside the uterine. Many factors are involved in the development of this disorder. Studies have shown that infectious agents due to the inflammation may predispose endometriosis. In this study the presence of human papillomavirus and herpes simplex virus types 1 and 2 were examined in endometriosis lesions. Material & Methods: This case-control study was performed in Sarem Women's Hospital. 40 paraffin-embedded blocks of endometriosis and 40 normal endometrial tissue blocks from patients without endometriosis were selected as control. After DNA extraction, molecular analysis was performed using polymerase chain reaction for diagnosis of mentioned infections. Results: The results of this study showed that, in investigation of papilloma infection, the virus DNA was found in one of the tissues of patients group (2.5%) and in 6 (15%) of healthy subjects. HSV infection was detected in 5 samples (12.5%) of the endometriosis tissues and 2 samples (5%) of control group. Conclusions: Findings of this research indicated that there is no significant association between papillomavirus and herpes simplex virus with endometriosis. In the other words, the presence of these viruses as factors that increase the risk of endometriosis incidence was not confirmed (P = 0.14 and P= 0.38, respectively), however further investigations are needed for the final conclusion.    },  
Keywords = {Endometriosis, Human Papillomavirus, Herpes Simplex Virus, Polymerase Chain Reaction},
volume = {7},
Number = {4}, 
pages = {480-487}, 
publisher = {Fasa University of Medical Sciences},
url = {http://jabs.fums.ac.ir/article-1-1230-en.html},  
eprint = {http://jabs.fums.ac.ir/article-1-1230-en.pdf},  
journal = {Journal of Advanced Biomedical Sciences},  
issn = {}, 
eissn = {2783-1523}, 
year = {2017}  
}

@article{ 
author = {Tanoorsaz, Saeed and Behpour, Naser and Tadibi, Vahi},  
title = {Investigating the Effect of Mid-Term of Aerobic Exercise on Apoptosis Biomarkers in the Cardiomyocytes of Streptozotocin-Induced Diabetic Rats}, 
abstract ={Background & Objective: Apoptosis plays a major role in the process of diabetes-induced heart disease, but the effects of aerobic intermediate exercises on the status of apoptosis in diabetics’ cardiomyocytes are unclear. The aim of this study was to investigate the effect of 4-week aerobic exercise on apoptosis biomarkers in the cardiomyocytes of Streptozotocin-induced diabetic rats. Material&Methods: 40 adult rats were randomly assigned to 4 groups, including: Control, Control¬+¬Diabetes, Exercise and Exercise + Diabetes. To induce diabetes intraperitoneal injection of Streptozotocin (STZ) solution (55mg/kg) was used. 14 days after STZ injection, the level of fasting blood glucose was measured by a glucometer. After confirming diabetes induction, the exercise protocol was performed for 4 weeks. The training groups ran for 4 weeks (5sessions/week) at a speed of 15-18 m/min and 25 to 44 minutes. 48 hours after the last training session, the subjects were anesthetized and the cardiac muscle was removed. The sFas, FasL and Bcl-2 were measured by ELISA. Results: Induction of diabetes in the control group, resulted in a significant increase in sFas and FasL levels and insignificantly increase in sFas/FasL and also insignificantly decrease in Bcl-2 levels (p<0.05).In non-diabetic groups, the implementation of 4 weeks of exercise training resulted in a significant decrease in sFas, FasL and a significant reduction of sFas/FasL and a significant increase in Bcl-2(p<0.05). Performing of 4 weeks of exercise training in diabetic groups also led to a nonsignificant decrease in sFas and sFas/FasL and a significant decrease in FasL and a nonsignificant increase in Bcl-2. Conclusion: The present study confirms the progressive effect of diabetes-induced apoptosis on heart. The results suggest that regular aerobic exercises may be used as a non-pharmacological strategy to reduce the complications of diabetes-induced apoptosis in the heart tissue of diabetic people.},  
Keywords = {Soluble Fas, Fas Ligand, Rodent Treadmill, Complications of Diabetes},
volume = {7},
Number = {4}, 
pages = {488-497}, 
publisher = {Fasa University of Medical Sciences},
url = {http://jabs.fums.ac.ir/article-1-1531-en.html},  
eprint = {http://jabs.fums.ac.ir/article-1-1531-en.pdf},  
journal = {Journal of Advanced Biomedical Sciences},  
issn = {}, 
eissn = {2783-1523}, 
year = {2017}  
}

@article{ 
author = {Sadeghi, Abdollah and NeshatGharamaleki, Mehrdad and Mohajeri, Daryoush},  
title = {Investigating the Protective effect of hesperetin in high fat diet-induced fatty liver disease in rat}, 
abstract ={Background & Objective: Fatty liver disease as the most common type of liver disease, is usually accompanied with obesity, hyperlipidemia, and diabetes mellitus Type 2. The aim of the present study was to evaluate the protective effects of Hesperetin on high fat diet-induced hepatic steatosis. Material & Methods: Thirty two Wistar male rats were treated in 4 experimental groups including: control group, high fat diet group, high fat diet plus Clofibrate as positive control, and high fat diet plus Hesperetin powder (5 mg/kg), at a period of 6 weeks. At the end of experiment, the groups were compared considering serum lipid profile, serum biomarkers of liver tissue injury and antioxidant activity of liver, using ANOVA test. Histopathology of liver was carried out for confirming the biochemical findings. Results: There were significant changes as shown by the results. In high fat diet group, hypertriglyceridemia, hypercholesterolemia, significant increased activities of hepatocellular enzymes (alanine aminotransferase, aspartate aminotransferase and alkaline phosphatase) in plasma, significant decline in antioxidants (superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase), and elevated lipid peroxidation indices in liver were seen (p<0.01). Hesperetin treatment significantly reduced elevated markers of liver tissue injury and marker of lipid peroxidation (malondialdehyde), and returned the liver antioxidants and the increased serum lipids towards normal (p<0.05). Histopathological examination of liver tissue was consistent with biochemical changes. Conclusion: The results showed that Hesperetin exerts protective effects against hepatic steatosis in rats fed with high fat diet through its antioxidant actions},  
Keywords = {Hesperetin, High fat diet, Fatty liver, Rats},
volume = {7},
Number = {4}, 
pages = {498-510}, 
publisher = {Fasa University of Medical Sciences},
url = {http://jabs.fums.ac.ir/article-1-1278-en.html},  
eprint = {http://jabs.fums.ac.ir/article-1-1278-en.pdf},  
journal = {Journal of Advanced Biomedical Sciences},  
issn = {}, 
eissn = {2783-1523}, 
year = {2017}  
}

@article{ 
author = {Sadoughi, Seyed Damoun and Edalatmanesh, Mohammad Amin and Rahbarian, Raheleh},  
title = {The Effect of Curcumin on Pituitary-Gonadal Axis, DNA Oxidative Damage and Antioxidant Enzymes Activity of Testicular Tissue in Male Diabetic Rats}, 
abstract ={Background & Objective: Diabetes causes reproductive disorders by endocrine glands dysfunction. Also curcumin has antioxidant and hypoglycemic properties. The purpose of this study was to determine the effect of curcumin on pituitary-gonadal axis, DNA oxidative damage and antioxidant enzymes activity of testicular tissue in male type one diabetic rats. Material & Methods: In this experimental study 40 male Wistar rats were allocated into 5 equal groups (n=8). Control group, non-treated diabetic group (30 days, intraperitoneal injection of dimethyl sulfoxide) and treated diabetic groups with doses 50, 100 and 150 mg/kg of curcumin (30 days, intraperitoneal injection of curcumin dissolved in dimethyl sulfoxide). Diabetes was induced using an intraperitoneal injection of 240 mg/kg alloxan. At the end of treatments, serum levels of LH, FSH, estrogen, testosterone, dihydrotestosterone and levels of SOD, CAT, GPX, HOdG-8 and MDA in testicle tissue were measured by ELISA. The statistical analysis was carried out using one-way ANOVA and post-hoc Tukey tests (p<0.05). Result: Compared to the non-treated diabetic group, administration of curcumin with doses of 100 and 150 mg/kg caused dose-dependent significant increased serum levels of LH, FSH, estrogen, testosterone and dihydrotestosterone, dose-dependent significant decreased HOdG-8 and MDA and also dose-dependent significant increased enzyme of SOD, CAT, and GPX in diabetic rats’ testicle (p<0.05). Conclusion: Administration of curcumin increases pituitary-gonadal axis activity, decreases lipid peroxidation and DNA oxidative damage and also increases antioxidant enzyme activity of testicular tissue in diabetic rats.  },  
Keywords = {Diabetes Mellitus, Curcumin, Testis, Antioxidant Enzymes, Rat},
volume = {7},
Number = {4}, 
pages = {511-520}, 
publisher = {Fasa University of Medical Sciences},
url = {http://jabs.fums.ac.ir/article-1-1287-en.html},  
eprint = {http://jabs.fums.ac.ir/article-1-1287-en.pdf},  
journal = {Journal of Advanced Biomedical Sciences},  
issn = {}, 
eissn = {2783-1523}, 
year = {2017}  
}

@article{ 
author = {Saghaei, Shahram and AbbasiMaleki, Saei},  
title = {Evaluation of the Effect of Coriandrum sativum L. Essentisal oil on Naloxone-Induced Jumping in Morphine-Dependent Mice}, 
abstract ={Background & Objective: Coriandrum sativum L (CS) has different pharmacological properties such as analgesic, anti-inflammatory, and anti-stress effects. Hence, in the present study the effects of CS essential oil on naloxone -induced jumping in morphine-dependent mice was investigated. Material & Methods: In this experimental study, 60 male albino mice were used. The animals were divided into 10 groups of 6, including carrier (10 ml/kg), clonidine (3.5 mg/kg), and different doses of CS essential oil (400, 600, and 800 mg/kg). Tolerance and dependency on morphine were induced by administration of different doses of morphine (50, 50, 75, and 50 mg/kg, respectively) in a 4-day schedule. On the last day, after administration of single dose of morphine, Naloxone (5 mg /kg) was injected and the number of jumps was recorded within 30 minutes.  Results: Results showed that all doses of CS essential oil and clonidine, compared to control group, significantly decreased the number of jumping in both tolerance and dependence stage (P<0.001).Also, only high (800mg/kg) and all doses of essential oil reduced the number of jumping during tolerance and dependence stages respectively, better than clonidine . Conclusion: Based on present study findings, it is concluded that, probably the existing linalool in CS could decrease the number of jumps from tolerance and dependence in morphine- dependent mice. Of course, further studies are required to clarify their exact mechanism of action.  },  
Keywords = {Coriandrum sativum L, Morphine, Naloxone, Physical dependence, Number of jumps, Mice},
volume = {7},
Number = {4}, 
pages = {521-529}, 
publisher = {Fasa University of Medical Sciences},
url = {http://jabs.fums.ac.ir/article-1-1467-en.html},  
eprint = {http://jabs.fums.ac.ir/article-1-1467-en.pdf},  
journal = {Journal of Advanced Biomedical Sciences},  
issn = {}, 
eissn = {2783-1523}, 
year = {2017}  
}

@article{ 
author = {Moghanibashi, Mehdi},  
title = {Investigating the Association between rs17859812 Polymorphism in MUC5AC Gene Promoter and Risk of Gastric Cancer}, 
abstract ={Background & Objective: MU5AC gene plays a key role in the maintenance of gastric mucosa against harmful factors in the stomach through encoding a main mucin of mucus lining gastric mucosa and its expression is reduced in the gastric cancer. In this study, due to the effect of genetic polymorphisms in the promoter region on the gene expression, the association between single nucleotide polymorphism of MU5AC gene promoter and the risk of gastric cancer was assessed. Materials & Methods: in this case-control study, a fragment of MUC5AC gene promoter was amplified by PCR technique in 50 individuals and rs17859812 single nucleotide polymorphism was selected by sequencing, and other subjects were genotyped using PCR-RFLP method. Finally, logistic regression and chi-square tests were used for data analysis. Results: Following sequencing and PCR-RFLP, the findings showed that allele C in the -221 of the promoter increased the risk of gastric cancer (OR= 1.66, CI= 3.09-5.18, p = 0.008) and CC genotype increased the risk of gastric cancer (OR= 4.66, CI= 2.09-10.38, p< 0.001). Also, CC + CT genotypes increased the risk of gastric cancer (OR=2.08, CI= 3.1-7.45 p= 0.007). Conclusion: The results of this study showed that allele C in the rs17859812 polymorphism of the MUC5AC gene is associated with the risk of gastric cancer. As this polymorphism is located in the vicinity of the glucocorticoid receptor binding site, it may affect the MUC5AC gene expression and may result in gastric cancer susceptibility.     },  
Keywords = {MUC5AC Gene, Gastric Mucosa, Gastric Cancer, Single Nucleotide Polymorphism, rs17859812},
volume = {7},
Number = {4}, 
pages = {530-537}, 
publisher = {Fasa University of Medical Sciences},
url = {http://jabs.fums.ac.ir/article-1-1222-en.html},  
eprint = {http://jabs.fums.ac.ir/article-1-1222-en.pdf},  
journal = {Journal of Advanced Biomedical Sciences},  
issn = {}, 
eissn = {2783-1523}, 
year = {2017}  
}

@article{ 
author = {Ehrampoush, Elham and Kouhpayeh, Seyed Amin and Farjam, Mojtaba and Homayounfar, Reza and Ghaemi, Alirez},  
title = {An Experience to develop and deliver Clinical Nutrition educational content for medical students}, 
abstract ={Background & Objective: The duty of physicians in the new world is to promote health, prevent diseases and deliver primary health care. But in accordance with the Edinburgh Declaration, physicians are not trained to deal with these issues. One of the key areas that has an important role in the health of the population, contains the issues related to life style and particularly nutritional issues. Proper nutrition plays a major role in achieving optimal health outcomes and inpatient health care costs will be reduced. This article describes the experience of the implementation and results of the evaluation of providing a course of clinical nutrition for medical students. Material & Methods: This action research study was conducted using census method, in collaboration with 50 students of Fasa University of Medical Sciences in the academic year 96-1395. In this study, clinical nutrition course was presented along with clinical courses for students. The data were gathered through pretest and posttest questionnaire, in each training session, and EDC questionnaire was applied to evaluate students' satisfaction. Descriptive statistics were used to analyze the results of the questionnaires. Results: The comparison of students' score after each training session with pre-test scores, showed a significant increase in students' knowledge of clinical nutrition. Most students' satisfaction was related to the presentation (4.37) and the use of resources (4.32), respectively. Conclusion: The results of this study demonstrated a positive effect of teaching clinical nutrition which can be considered by policymakers to insert this topic in the clinical course for medical students.  },  
Keywords = {Clinical nutrition, medical student, training},
volume = {7},
Number = {4}, 
pages = {538-548}, 
publisher = {Fasa University of Medical Sciences},
url = {http://jabs.fums.ac.ir/article-1-1498-en.html},  
eprint = {http://jabs.fums.ac.ir/article-1-1498-en.pdf},  
journal = {Journal of Advanced Biomedical Sciences},  
issn = {}, 
eissn = {2783-1523}, 
year = {2017}  
}

@article{ 
author = {Zanjani, Maryam and Yazdi-Ravandi, Saeid and Shahmohammadi, Sahar},  
title = {Clinical application of Bender–Gestalt in screening of brain lesions in patients with Stroke and Multiple Sclerosis}, 
abstract ={Background & Objective: Bender-gestalt test is often discussed as a screening method in different brain damages including organic brain syndrome, schizophrenia and neuropsychological functions. The purpose of this study is to investigate clinical application of Bender–Gestalt in screening of brain lesions in patients with Stroke and Multiple Sclerosis. Material & Methods: In this descriptive–analytic research, 21 patients with multiple sclerosis and 19 stroke patients and 30 healthy people were studied through convenience method. Data were collected using Bender-gestalt test and demographic questionnaire checklist including age, gender and the number of years of disease. Collected data were analyzed through SPSS-16 software. Results: 23.8% patients with multiple sclerosis, 36.8% patients with stroke and 43.3% control group people were men. Three basic indices: hand tremors (89.5), pencil pressure (73.7) and bold lines and redrawing in stroke patients and two basic indices: pencil pressure (47.6) and hand tremors (42.9) had the most frequency in patients with multiple sclerosis. Stroke patients had the most accurate (26.3) drawings in card number 1 while patients with multiple sclerosis in card numbers 1–2 and 5 had above 50% accurate drawings. Conclusion: Patients with Multiple sclerosis had better performance on running Bender test in comparison with stroke patients. Hand tremors and pencil pressure indices are most important ones which can be used in the identification of patients with multiple sclerosis and stroke patients.},  
Keywords = {Bender-gestalt, Stroke, Multiple sclerosis, Brain lesion, Screening},
volume = {7},
Number = {4}, 
pages = {549-556}, 
publisher = {Fasa University of Medical Sciences},
url = {http://jabs.fums.ac.ir/article-1-1362-en.html},  
eprint = {http://jabs.fums.ac.ir/article-1-1362-en.pdf},  
journal = {Journal of Advanced Biomedical Sciences},  
issn = {}, 
eissn = {2783-1523}, 
year = {2017}  
}

@article{ 
author = {Haghnegahdar, Abdolaziz and Tadayon, Mehran and Golkari, Ali},  
title = {Assessing the knowledge and attitude of general dentists concerning Infection control principles during preparing intra oral radiographic views in Marvdasht, Fasa and Kazeroon}, 
abstract ={Background & Objective: Both dental patients and workers are in high chance of exposure to infective diseases such as HIV and Hepatitis. In spite of the advances in infection control technologies, there are still many problems in both private and state dental centers. The purpose of this study was to assess the knowledge and attitude of general dentists of Marvdasht, Fasa and Kazeroon cities concerning infection control principles during preparing intra oral radiographic views. Material & Methods: This is a cross-sectional analytical study. Studied society was dentists of Fasa, Marvdasht and Kazeroon.15 dentists were collected randomly in each city. Data were collected using questionnaire. Results were analyzed using One-Way ANOVA (Analysis of variance), Student’s T-test and Pearson’s correlation coefficient tests. Results: Knowledge average scores were 5.66 in Fasa, 6.4 in Marvdasht, 4.06 in Kazeroon and 5.37 in total (out of 12). Attitude average scores were 6.2 in Fasa, 6.86 in Marvdasht, 5.06 in Kazeroon and 6.04 in total (out of 12). Knowledge of dentists in Marvdasht was significantly higher than Kazeroon. The knowledge and attitudes of dentists about infection control principles during preparing intra oral radiographic views was not in good range. Conclusion: More emphasis of the aspect of infection control principles is necessitated during preparing intra oral radiographic views In order to improve knowledge and correcting attitudes of dentists during dentistry training courses.},  
Keywords = {Knowledge, Attitude, Infection control, Intra oral radiography},
volume = {7},
Number = {4}, 
pages = {565-572}, 
publisher = {Fasa University of Medical Sciences},
url = {http://jabs.fums.ac.ir/article-1-635-en.html},  
eprint = {http://jabs.fums.ac.ir/article-1-635-en.pdf},  
journal = {Journal of Advanced Biomedical Sciences},  
issn = {}, 
eissn = {2783-1523}, 
year = {2017}  
}

@article{ 
author = {Kazemzadeh, Samira and Babaei, Esmaeil and Hoseinpourfizi, Mohammad ali},  
title = {Investigating the expression of CCAT2 gene as a new molecular marker in breast tumors}, 
abstract ={Background & Objectives: lnc-CCAT2 is a non-protein coding RNA, which is highly expressed in tissues and cancer cell types. Due to the increasing incidence of breast tumors in recent years, in this research, the qualification of CCAT2 gene expression is assessed as a potential molecular marker in the diagnosis and treatment of breast tumors. Material & Methods: Totally, 35 breast tumor specimens and 35 non-tumoral ones related to the tumor margins were studied using quantitative real-time PCR method. Gene β2m was used as the internal control. Obtained results were statistically analyzed Using the SPSS and sigmaplot software. Results: The results showed that CCAT2 gene expression, significantly increased in breast tumor samples compared to marginal non-tumor specimens. (P < 0.01) Conclusion: This results showed that CCAT2 gene can be applied as a diagnostic marker for the identification and diagnosis of breast tumor tissues and non-tumor types. Therefore, it can be used alongside other conventional Diagnostic Laboratorial methods. More studies are underway on the biomarking potentiality of this gene.},  
Keywords = {Breast cancer, Non-coding RNA, Real-time PCR, CCAT2},
volume = {7},
Number = {4}, 
pages = {573-581}, 
publisher = {Fasa University of Medical Sciences},
url = {http://jabs.fums.ac.ir/article-1-1212-en.html},  
eprint = {http://jabs.fums.ac.ir/article-1-1212-en.pdf},  
journal = {Journal of Advanced Biomedical Sciences},  
issn = {}, 
eissn = {2783-1523}, 
year = {2017}  
}