<?xml version="1.0" encoding="utf-8"?>
<journal>
<title>Journal of Advanced Biomedical Sciences</title>
<title_fa>مجله علوم زیست پزشکی پیشرفته</title_fa>
<short_title>J Adv Biomed Sci.</short_title>
<subject>Medical Sciences</subject>
<web_url>http://jabs.fums.ac.ir</web_url>
<journal_hbi_system_id>1</journal_hbi_system_id>
<journal_hbi_system_user>admin</journal_hbi_system_user>
<journal_id_issn>2228-5105</journal_id_issn>
<journal_id_issn_online>2783-1523</journal_id_issn_online>
<journal_id_pii>8</journal_id_pii>
<journal_id_doi>7</journal_id_doi>
<journal_id_iranmedex></journal_id_iranmedex>
<journal_id_magiran></journal_id_magiran>
<journal_id_sid>14</journal_id_sid>
<journal_id_nlai>8888</journal_id_nlai>
<journal_id_science>13</journal_id_science>
<language>en</language>
<pubdate>
	<type>jalali</type>
	<year>1403</year>
	<month>6</month>
	<day>1</day>
</pubdate>
<pubdate>
	<type>gregorian</type>
	<year>2024</year>
	<month>9</month>
	<day>1</day>
</pubdate>
<volume>14</volume>
<number>4</number>
<publish_type>online</publish_type>
<publish_edition>1</publish_edition>
<article_type>fulltext</article_type>
<articleset>
	<article>


	<language>en</language>
	<article_id_doi></article_id_doi>
	<title_fa>اثر پروبیوتیک ها در کاهش 3-مونوکلروپروپان-1، 2-دیول (3-MCPD) در ماتریکس شیر خشک آلوده به غلظت های مختلف -MCPD3</title_fa>
	<title>The Effect of Probiotic Bacteria on the Reduction of 3-Monochloropropane-1,2-Diol (3-MCPD) in Powdered Infant Formula</title>
	<subject_fa>میکروبیولوژی (صنایع غذایی)</subject_fa>
	<subject>Microbiology (Food Industry)</subject>
	<content_type_fa>پژوهشي</content_type_fa>
	<content_type>Research</content_type>
	<abstract_fa></abstract_fa>
	<abstract>&lt;div style=&quot;text-align: justify;&quot;&gt;&lt;span style=&quot;font-size:11pt&quot;&gt;&lt;span style=&quot;line-height:normal&quot;&gt;&lt;span style=&quot;tab-stops:right 14.15pt 56.7pt left 107.25pt&quot;&gt;&lt;span style=&quot;unicode-bidi:embed&quot;&gt;&lt;span sans-serif=&quot;&quot; style=&quot;font-family:Calibri,&quot;&gt;&lt;b&gt;&lt;u&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:#2f5496&quot;&gt;Background &amp; Objectives:&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/u&gt;&lt;/b&gt;&lt;b&gt; &lt;/b&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;3-Monochloropropane-1,2-diol (3-MCPD) is a chemical contaminant found in many food products, including infant formulas. Given the vital contribution of milk and its products to the human diet, particularly for children, the presence of 3-MCPD in dairy products poses a significant public health concern. Therefore, it is crucial to explore natural compounds for 3-MCPD removal. This study investigates the effect of probiotic microorganisms (&lt;em&gt;Lactobacillus plantarum, Lactobacillus murinus, and Yarrowia lipolytica&lt;/em&gt;) on reducing 3-MCPD levels in infant formula containing various 3-MCPD concentrations.&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;font-size:11pt&quot;&gt;&lt;span style=&quot;line-height:normal&quot;&gt;&lt;span style=&quot;tab-stops:right 14.15pt 56.7pt left 107.25pt&quot;&gt;&lt;span style=&quot;unicode-bidi:embed&quot;&gt;&lt;span sans-serif=&quot;&quot; style=&quot;font-family:Calibri,&quot;&gt;&lt;b&gt;&lt;u&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:#2f5496&quot;&gt;Materials &amp; Methods:&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/u&gt;&lt;/b&gt;&lt;b&gt; &lt;/b&gt;&lt;em&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;L. plantarum, L. murinus&lt;/span&gt;&lt;/em&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt; bacteria, and &lt;em&gt;Y. lipolytica&lt;/em&gt; yeast were prepared as active cultures. Subsequently, various 3-MCPD concentrations were added to the infant formula, and the effect of the bacteria and the yeast on 3-MCPD reduction was investigated using gas chromatography with flame ionization detection (GC-FID).&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;font-size:11pt&quot;&gt;&lt;span style=&quot;line-height:normal&quot;&gt;&lt;span style=&quot;tab-stops:right 14.15pt 56.7pt left 107.25pt&quot;&gt;&lt;span style=&quot;unicode-bidi:embed&quot;&gt;&lt;span sans-serif=&quot;&quot; style=&quot;font-family:Calibri,&quot;&gt;&lt;b&gt;&lt;u&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:#2f5496&quot;&gt;Results:&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/u&gt;&lt;/b&gt;&lt;b&gt; &lt;/b&gt;&lt;em&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;L. plantarum, L. murinus, and Y. lipolytica&lt;/span&gt;&lt;/em&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt; demonstrated the ability to reduce 3-MCPD levels in the infant formula at different concentrations and contact times. &lt;em&gt;L. plantarum and Y. lipolytica&lt;/em&gt; were found to be more effective in reducing 3-MCPD in the infant formula compared to &lt;em&gt;L. murinus&lt;/em&gt;.&lt;/span&gt;&lt;/span&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;font-size:11pt&quot;&gt;&lt;span style=&quot;line-height:normal&quot;&gt;&lt;span style=&quot;text-autospace:none&quot;&gt;&lt;span style=&quot;unicode-bidi:embed&quot;&gt;&lt;span sans-serif=&quot;&quot; style=&quot;font-family:Calibri,&quot;&gt;&lt;b&gt;&lt;u&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:#2f5496&quot;&gt;Conclusion:&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/u&gt;&lt;/b&gt;&lt;b&gt; &lt;/b&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;The results indicate that &lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;probiotic bacteria can effectively mitigate the toxic effect of 3-MCPD. These findings have potential applications in the food industry, particularly in dairy products.&lt;/span&gt;&lt;/span&gt;&lt;span style=&quot;font-size:12.0pt&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;span style=&quot;color:black&quot;&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/div&gt;</abstract>
	<keyword_fa></keyword_fa>
	<keyword>Infant formulas, 3-monochloropropane-1, 2-diol, Probiotics, Gas chromatography</keyword>
	<start_page>295</start_page>
	<end_page>300</end_page>
	<web_url>http://jabs.fums.ac.ir/browse.php?a_code=A-10-3399-1&amp;slc_lang=en&amp;sid=1</web_url>


<author_list>
	<author>
	<first_name>Elnaz</first_name>
	<middle_name></middle_name>
	<last_name>Sharyat</last_name>
	<suffix></suffix>
	<first_name_fa>الناز</first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa>شریعت</last_name_fa>
	<suffix_fa></suffix_fa>
	<email>sharyat.elnaz@gmail.com</email>
	<code>100319475328460029322</code>
	<orcid>0009-0003-7436-3752</orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Department of Microbiology, Karaj Branch, Islamic Azad University, Karaj, Iran</affiliation>
	<affiliation_fa>گروه میکروبیولوژی، واحد کرج، دانشگاه آزاد اسلامی، کرج، ایران</affiliation_fa>
	 </author>


	<author>
	<first_name>Ladan</first_name>
	<middle_name></middle_name>
	<last_name>Rashidi</last_name>
	<suffix></suffix>
	<first_name_fa>لادن</first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa>رشیدی</last_name_fa>
	<suffix_fa></suffix_fa>
	<email>l.rashidi@standard.ac.ir</email>
	<code>100319475328460029323</code>
	<orcid>100319475328460029323</orcid>
	<coreauthor>Yes
</coreauthor>
	<affiliation>Department of Food and Agricultural Products, Food Technology and Agricultural Products Research Center, Standard Research Institute (SRI), Karaj, Iran</affiliation>
	<affiliation_fa>گروه مواد غذایی و محصولات کشاورزی، تحقیقات فناوری غذایی و محصولات کشاورزی مرکز، پژوهشکده استاندارد (SRI)، کرج، ایران</affiliation_fa>
	 </author>


	<author>
	<first_name>Naser</first_name>
	<middle_name></middle_name>
	<last_name>Harzandi</last_name>
	<suffix></suffix>
	<first_name_fa>ناصر</first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa>هرزندی</last_name_fa>
	<suffix_fa></suffix_fa>
	<email>m.b9854@yahoo.com</email>
	<code>100319475328460029324</code>
	<orcid>100319475328460029324</orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Department of Microbiology, Karaj Branch, Islamic Azad University, Karaj, Iran</affiliation>
	<affiliation_fa>گروه میکروبیولوژی، واحد کرج، دانشگاه آزاد اسلامی، کرج، ایران</affiliation_fa>
	 </author>


</author_list>


	</article>
</articleset>
</journal>
