en سنتز سبز نانوذرات SnO2 با طلا با استفاده از عصاره گیاه کلپوره برای ارزیابی خواص فیزیکوشیمیایی و ضد باکتریایی آنها نانوتکنولوژی پزشکی Nanomedicine پژوهشي Research <div style="text-align: justify;"><span style="font-size:12pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span style="color:#2f5496">Background & Objective:</span></b> The biological production of nanoparticles (NPs) is a technique that has garnered a lot of interest because it is inexpensive, straightforward, and friendly to the natural environment. This study explores the green synthesis of Au-doped SnO₂ NPs using Teucrium polium plant extract and evaluates their antimicrobial properties in comparison with two commonly used antibiotics.</span></span></span></span></div> <div style="text-align: justify;"><span style="font-size:12pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span style="color:#2f5496">Materials & Methods:</span></b> Initially, an extract of Teucrium polium was made using water, and then it was combined with solutions of tin (II) chloride dehydrate [SnCl₂.2H₂O] and gold (III) chloride trihydrate [HAuCl₄.3H₂O]. The crystal structure was studied using X-ray diffraction (XRD). The form, structure, and grain size of the NPs were analyzed using scanning electron microscope (SEM) and transmission electron microscope (TEM). The synthesized NPs were tested for their antibacterial properties.</span></span></span></span></div> <div style="text-align: justify;"><span style="font-size:12pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span style="color:#2f5496">Results:</span></b> The XRD and EDS analyses revealed that the SnO₂:Au phase formed an average crystallite size of 22 nm and an Au dopant content of around 2%. The SEM and TEM investigations demonstrated that the NPs were formed in a regular and nanoscale manner, with diameters ranging from 25 to 30 nm. MIC and MBC of SnO₂: Au NPs against the studied bacteria(S.aureus ATCC 43300, P.aeruginosa PAO1) were reported 9.6&plusmn;0.13- 9.6&plusmn;0.07 &mu;g/mL and 25.9&plusmn;11.5- 32.5&plusmn;11.2 &mu;g/mL</span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span style="color:#2f5496">Conclusion:</span></b> Green-synthesized NPs exhibit significant antimicrobial activity against both Gram-positive and Gram-negative bacteria, even at low concentrations. The NPs effectively eliminate bacteria and prevent biofilm formation.</span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span style="color:#2f5496"></span></b></span></span></span></span><br> &nbsp;</div> Teucrium polium, Green synthesis, SnO2: Au NPs, Structural analysis Antimicrobial 148 157 http://jabs.fums.ac.ir/browse.php?a_code=A-10-2901-3&slc_lang=en&sid=1 Merat Karimi مرات کریمی sdgh@kashanu.ac.ir 100319475328460027506 100319475328460027506 No Institute of Nanoscience and Nanotechnology, University of Kashan, Kashan, Iran پژوهشگاه علوم و فناوری نانو، دانشگاه کاشان، کاشان، ایران Ehsan Sadeghi احسان صادقی sdgh@kashanu.ac.ir 100319475328460027507 100319475328460027507 Yes Institute of Nanoscience and Nanotechnology, University of Kashan, Kashan, Iran پژوهشگاه علوم و فناوری نانو، دانشگاه کاشان، کاشان، ایران Mostafa Zahedifar مصطفی زاهدی فر zhdr@kashanu.ac.r 100319475328460027508 100319475328460027508 No Institute of Nanoscience and Nanotechnology, University of Kashan, Kashan, Iran پژوهشگاه علوم و فناوری نانو، دانشگاه کاشان، کاشان، ایران