Journal of Advanced Biomedical Sciences
مجله علوم زیست پزشکی پیشرفته
JABS
Medical Sciences
http://jabs.fums.ac.ir
1
admin
2228-5105
2783-1523
8
7
14
8888
13
en
jalali
1399
8
1
gregorian
2020
11
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10
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online
1
fulltext
fa
مقایسه دز جذبی ریه و شاخصهای انطباق و همگنی تومور سینه در بیماران مستکتومی شده با استفاده از میدانهای فوتونی و الکترونی
Comparing the Absorbed dose of Lung and Conformity and Heterogeneity Indexes of Breast Tumor for Mastectomy Patients Using Photon and Electron Beams
فیزیک پزشکی
Medical Physics
پژوهشي
Research
<div style="text-align: justify;"><strong><em>Background & objective: </em></strong>The aim of this study is to evaluate the feasibility of using electron therapy as main treatment modality of mastectomy patients and determine the absorbed dose of lung and heterogeneity and conformity indexes of breast region in this technique and compare it with the conventional method of applying tangential photon beams.<br>
<strong><em>Materials & methods:</em></strong> In this study, the CT images of 10 mastectomy patients were used. The CT images were imported into Monaco treatment planning system. Targets and organs at risk were contoured by a radiation oncologist. Then, for each patient, two treatment plans were designed: one with photon fields and the other with electron fields. The prescription dose for each plan was 50 Gy and the plans were designed in a way to deliver 90% of prescription to at least 90% of target volume. Conformity and heterogeneity indexes and absorbed dose of lung were then evaluated and compared.<span dir="RTL"></span><br>
<strong><em>Results:</em></strong> Comparing the obtained data, it was shown that photon fields provided better conformity and heterogeneity compared to electron fields. Also, due to the different irradiation angles of photon and electron fields, in most patients, photon fields led to lower absorbed dose of lung.<br>
<strong><em>Conclusion:</em></strong> The results of this study showed that in terms of sparing lung and delivering a homogeneous and conformal dose to tumor, radiotherapy of mastectomy cases with tangential photon fields have better results compared to electron therapy.<br>
</div>
Breast cancer, Electron therapy, Conformity index, Heterogeneity index, Absorbed dose
3065
3073
http://jabs.fums.ac.ir/browse.php?a_code=A-10-700-2&slc_lang=fa&sid=1
Davod
Borji
داود
برجی
borji@yahoo.com
100319475328460024826
100319475328460024826
No
Department of Medical Radiation Engineering, Central Tehran Branch, Islamic Azad University, Tehran, Iran
گروه مهندسی هستهای، مهندسی پرتو پزشکی، واحد تهران مرکزی، دانشگاه آزاد اسلامی، تهران، ایران
Nooshin
Banaee Rezaeeyeh
نوشین
بنائی رضائیه
nooshin_banaee@yahoo.com
2755553995
100319475328460024827
Yes
Medical Radiation Research Center, Central Tehran Branch, Islamic Azad University, Tehran, Iran
مرکز تحقیقات پرتو پزشکی، واحد تهران مرکزی، دانشگاه آزاد اسلامی، تهران، ایران
Hassan Ali
Nedaie
حسنعلی
ندایی
nedaieha@sina.tums.ac.ir
100319475328460024828
100319475328460024828
No
Department of Biophysics, Faculty of Medicine Tehran University of Medical Sciences, Tehran, Iran
گروه فیزیک پزشکی و مهندسی پزشکی، دانشکده پزشکی، دانشگاه علوم پزشکی تهران، تهران، ایران