en نانوذرات پلی لاکتیک اسید: نویدی برای مبارزه با سرطان نانوتکنولوژی پزشکی Nanomedicine مروری Review <div style="text-align: justify;">Nanoparticles are used mainly for the transmission of the therapeutic molecules (like drugs, proteins, or DNA) to the organ/tissue of human body. Polymeric nanoparticles are mostly applied for therapeutic effectiveness in cancer therapy. The micro environment of tumor tissues in vessels can assist nanoparticles in achieving their anticipated accumulation. Poly (lactic acid)(PLA) is a novel green polymer with natural sources (like sweet potato and sugar cane). PLA is a linear aliphatic which has great sustainability, renewability and compostability. PLA has popper mechanical, thermal and barrier properties. This biomaterial is thermoplastic polyester with biocompatibility, non-toxicity and biodegradability. Various forms of PLA nanoparticles are synthetized for biomedical applications like cancer treatments and wound healing process. This review article introduces the various structures of polylactic acid nanoparticles used to deliver anticancer drugs. Furthermore, the investigational approaches that are considered for using PLA nanoparticles in treatment of different types of cancers will be reported briefly.<br> &nbsp;</div> Poly (Lactic Acid), Polymeric Nanoparticle, Cancer Treatment, Drug Deliver, Gene Delivery, Tumor Cell 3791 3814 http://jabs.fums.ac.ir/browse.php?a_code=A-10-2559-1&slc_lang=en&sid=1 Farnaz Fattahi فرنازالسادات فتاحی fattahi_farnaz@yahoo.com 100319475328460026342 100319475328460026342 Yes Department of Textile Engineering, Isfahan University of Technology, Isfahan, Iran گروه مهندسی نساجی، دانشگاه صنعتی اصفهان، اصفهان، ایران Tahereh Zamani طاهره زمانی zamani.tahere@iran.ir 100319475328460026343 100319475328460026343 No The Genetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran مرکز تحقیقات ژنتیک، دانشگاه علوم بهزیستی و توانبخشی، تهران، ایران