TY - JOUR JF - JABS JO - JABS VL - 10 IS - 1 PY - 2020 Y1 - 2020/4/01 TI - Evaluation of Relationship between Blood Concentration of Vitamin D and Ejection Fraction, Homocysteine, Calcium and CRP in Bushehr Heart Center TT - بررسی همسویی بین سطح سرمی ویتامین D˛ هموسیستئین، CRP و کلسیم خون با آترواسکلروز عروق کرونر و کسر تخلیه ای بطن چپ (Ejection Fraction)در مرکز قلب بوشهر N2 - Background & Objective: The aim of this study was to evaluate the association between blood concentration of vitamin D and cardiovascular diseases, with regard to the percentage of ejection fraction, the number of coronary artery blockage, concentration of homocysteine, CRP and Ca. Materials & Methods: In this case-controlled investigation, 433 people who referred to Bushehr Heart Center for medical examination participated. Based on the preliminary results of clinical tests including ECG, echocardiogram, and angiography, the participants were selected and divided into case and control groups. Venous blood samples were collected (10 ccs) and immediately centrifuged and the serum samples were separated and stored at -80 ᵒC until analysis. The ejection fraction was recorded and the serum samples were processed for the measurement of 25-hydroxyvitamin D, homocysteine, calcium and CRP concentration. Results: The mean concentration of vitamin D in the serum of case group was significantly lower than that of the control. Moreover, the mean percentage of EF in the control group was significantly higher than that of the control group. Furthermore, the serum level of vitamin D and the atherosclerosis of coronary arteries were inversely correlated. Moreover, the mean concentration of CRP was significantly higher in the case group than in the control gorup. Conclusion: The result of this study showed that low serum levels of vitamin D may be related to cardiovascular disease. Moreover, vitamin D levels were inversely associated with the number of atherosclerotic arteries in men only. SP - 2061 EP - 2069 AU - Iranpour, Dariush AU - Bahremandjou, saba AU - Motamed, Niloufar AU - hajian, najmeh AU - rahimi, rahimeh AU - Movahed, ali AD - The Persian Gulf Tropical Medicine Research Center, Departments of Biochemistry, Bushehr University of Medical Sciences, Bushehr, Iran KW - vitamin D KW - Ejection fraction KW - Coronary Atherosclerosis KW - coronary artery disease UR - http://jabs.fums.ac.ir/article-1-1912-en.html ER -