Showing 36 results for Raining
Ebrahim Heydari Kochi, Esmaeil Heydari Kochi,
Volume 1, Issue 2 (9-2011)
Abstract
Background & Objective: Nitrate is one of the contaminants of groundwater resources that has had a growing trend in recent decades as the result of human activities such as agriculture, irregular utilization of groundwater aquifers, and non-systematic disposal of urban and industrial sewage. The increase of nitrate higher than the limit causes several health problems such as Methemoglobinemia, formation of Nitrosamine compounds and potential risks in pregnant women. Now, from among 400 wells of drinking water in Tehran, only 2 percent, that is 8 wells, have Nitrate above the limit (50mg/lit). The purpose of this study is to measure the rate of Nitrate in drinking water in rural areas of Fasa city during the years 2007 to 2008 and finding its relation with the rate of rainfall. Considering the lack of surface waters in Fasa city, almost all water requirements of the people are supplied from underground wells.
Materials & Methods: This research has been conducted during the years 2007-2008. In this period, 288 samples from among 38 wells (including 24 deep well, 14 hand-made well) were selected and the rate of nitrate was measured using Espectrophotometer.
Results: The obtained results indicate that in the years 2007, 2008, the maximum rate of rainfall was in winter, respectively with 94.3 and 36.6mm. and its minimum rate was in summer, respectively with 1.2 and 0.1mm, while the maximum rate of Nitrate during these years was in summer, respectively with 27.13, 27.88mg/lit and its minimum rate was in winter, respectively with 22.89 and 25.35 mg/lit. Also, the rate of rainfall in year 2007 was 168mm, which has been decreased to 57.7mm in 2008, during this period the average rate of Nitrate has been increased from 25.39 to 26.64 that this increase was more evident in hand-made wells, so that it has been increased from 37.7 in 2007 to 40.40mg/lit in 2008.
Conclusion: The purpose of this study is to determine if there is any relationship between the rate of rainfall and Nitrate level in groundwater. The results of this study have shown that by the decrease of rainfall, the rate of Nitrate in the groundwater is increased in the studied region. Considering the recent drought and the decrease of atmospheric precipitations, the control of factors such as agriculture, urban and industrial sewage around wells and irregular utilization of groundwater aquifers should be considered more.
Ar Kazemi, H Agha Alinejad, R Eslami, P Ehsan, R Baghaei, R Dabaghzadeh, M Ghanbarzadeh,
Volume 5, Issue 3 (11-2015)
Abstract
Background & Objectives: Breast cancer is nowadays one of the most harmful threats to women’s health. However, exercise training plays an adjuvant role in breast cancer (Adjuvant also means preventive. So, no need to repeat preventing.). Therefore, the aim of this study is to investigate the effect of 6-week endurance training on the levels of interleukin-8 in the tumor and Interleukin-17 in the serum of mice suffering from breast cancer.
Materials & Methods: In this study, 20 female Balb/C mice were randomly divided into exercise-tumor (RET) and rest-tumor (RRT) groups. The mice were oriented in the environment, and one million estrogen-dependent breast cancer cells (MC4L2) were injected into the top of the right thigh of each mouse. Subsequently, the RET group performed the endurance exercise 5 days per week for 6 weeks. The tumor volume was measured by a digital caliper each week. Finally, the mice were sacrificed, and the tumor tissue was removed and kept in -70°C. Then, ELISA method was performed and the data were collected.
Results: After 6 weeks of training, a significant decrease was observed in the RTE group in the serum level of IL-17 and IL-8 protein in tumor (P< 0.05). These results were consistent with the tumor growth rate.
Conclusion: The findings of the present study indicate that endurance training can reduce IL-8 and IL-17 proteins in the tumor and serum of mice ill with breast cancer. Therefore, the physical activity is utilized as an important factor in the improvement of adjutant therapy along with other therapeutic methods to treat breast cancer.
Azadeh Nabizadeh Haghighi, Ramin Shabani,
Volume 5, Issue 4 (12-2015)
Abstract
Background & Objectives: Non-alcoholic fatty liver disease, characterized by the deposition of fat in liver cells, can cause fibrosis, cirrhosis, and liver cell damage if not controlled. The aim of this study is to compare the effects of medication therapy and exercise training with diet on liver enzyme levels and liver sonography in patients with non-alcoholic fatty liver disease (NAFLD).
Materials & Methods :In this quasi-experimental study, female patients with non-alcoholic fatty liver were randomly divided into two groups: medication therapy (n = 10) and exercise therapy (n = 10) for 8 weeks. During this period, the exercise group performed exercise training three days a week for 90 minutes per session. The drug was given to the medication group. In both groups, the diet was 500 calories less than their daily energy. Before and after intervention, blood tests and liver sonography were executed. All statistical analyses were done using SPSS for Windows version 20. Comparisons between and within groups were performed by Student's t-test and Wilcoxon test on paired and unpaired data. P < 0.05 was considered statistically significant.
Results :In both groups, liver enzyme levels and disease severity in sonography reduced significantly (p<0.05).
Conclusion: The findings of the present research showed that both methods of therapy have the same effect on reducing the severity of NAFLD.
Babak Farzad, Hamid Rajabi, Seyed Behnamedin Jameie, Reza Gharakhanlou, Parisa Hayat, Farinaz Nasiri Nejad, . Sima Damani,
Volume 6, Issue 2 (8-2016)
Abstract
Background & Objective: Unknown mechanisms are involved in neuropathic pain. Among the non-pharmacological treatments, it seems that physical activity improves neuropathic pain. However, the possible reasons for the effectiveness of regular physical activity on neuropathic pain are unknown. Therefore, the present study was performed to determine the effects of two-week swimming training on the expression of GAD65 enzyme and P2X3 receptor in Chronic Constriction Injury (CCI) of the sciatic nerve.
Materials & Methods: 40Wistar adult rats were divided into five groups randomly: 1) CCI neuropathic pain with swimming training (CCIST2); 2) CCI neuropathic pain without swimming training (CCI); 3) No CCI neuropathic pain with swimming training (ST2); No CCI neuropathic pain without swimming training (control group); 5) CCI sham surgery (Sham CCI). CCI and CCIST2 groups underwent peripheral nerve injury by four loose ligatures around sciatic nerve. Swimming program included two weeks with five sessions per week, and 30-60 min per session. The protein expressions of GAD65 enzyme and P2X3 receptor were evaluated by western blotting technique.
Results: CCI surgery decreased the expression of GAD65, but two weeks swimming training increased expression of GAD65 comparing to CCI and Sham CCI groups (P≤0.001), but P2X3 receptor expression were not significantly different among groups in lumbar segment of rats (P>0.05).
Conclusion: Totally, our findings showed that two-week swimming training improves neuropathic pain possibly through maintenance of inhibitory neurons and subsequently increased GAD65, which converts glutamate excitatory neurotransmitter to GABA inhibitory neurotransmitter.
Abdolreza Kazemi, Behjat Kalantari Khandani, Afsoon Ashraf Ganjoei,
Volume 6, Issue 2 (8-2016)
Abstract
Background & Objective: The regular exercise training is known as a preventive and adjuvant therapy in inflammatory diseases such as cancer. The aim of this study was to determine the effect of the aerobic training on IL-10 and IL-8 levels and the count of white blood cells (WBC) in women with breast cancer.
Material & Methods: The statistical society of the present study included Kerman women with breast cancer. Forty patients with breast cancer were randomly divided into two groups: exercise (n = 20) and control (n = 20). The exercise group performed the endurance training for 8 weeks with the intensity between 40 to 55 percent of the target heart rate. Twenty four hours before the first session and 48 hours after the last session of the exercise protocol, blood samples were taken from both groups and then IL-10 and IL-8 levels in serum were measured by ELISA via a Boster kit.
Results: The results of the present study showed that 8 weeks of the endurance exercise training did not significantly increase the IL-10 (P=0.113) serum level, but increased the WBC count (p=0.019) and decreased the serum level of IL-8 (p=0.03) significantly.
Conclusion: According to the results of the present study, regular endurance training via decreasing the inflammatory factors can be considered as an effective factor along with other therapies in improving breast cancer.
Abdolreza Kazemi, Jamileh Kermani, Masoud Rahmati,
Volume 6, Issue 3 (11-2016)
Abstract
Background & Objective: Adaptations in neuromuscular system are due to changes in the expression and activity of proteins and its transmitters. JIP 3 protein plays a role in the regulation of structure and function of neurons as well as the establishment of multi-nuclear muscle cells. Considering the effects of exercise on neuromuscular system, the present study aimed to investigate the effects of 6 weeks of endurance training on JIP3 gene expression in soleus muscle of male Wistar rats.
Material & Methods: Ten Wistar male rats were randomly assigned in two groups: trained and control. Endurance training protocol was performed for 6 weeks. Forty eight hours after final training session, the rats were dissected, and soleus muscle was removed. JIP3 gene expression was performed through Real Time PCR method.
Results: Endurance training increased JIP3 gene expression significantly compared to the control group.
Conclusion: It appears that a period of endurance training increases intramuscular gene expression of JIP3 through this can lead to a better consistency and functionality in the muscles.
Seyed Ali Hoseini, Abdosaleh Zar, Seyed Ali Hoseini, Ghobad Hassanpour, Maryam Kheirdeh, Mehdi Noura,
Volume 6, Issue 3 (11-2016)
Abstract
Background & Objective: Narcotics abuse can induce liver disorders; nevertheless, exercises improve liver disorders. The present research aimed to review the effect of eight weeks forced swimming training with methadone supplementation on liver enzymes of rats.
Material & Method: In this experimental research, 48 rats were selected, and after one week adaptation to lab environment, they were randomly divided into four groups of 12 rats including (1) forced swimming training, (2) methadone supplementation, (3) forced swimming training with methadone supplementation, and (4) control. Groups 2 and 3 used 2 mg/kg methadone daily for 8 weeks. Also, groups 1 and 3 swam for 8 weeks, three sessions per week and each session for 30 minutes. For statistical analysis of data, one way ANOVA and Tukey post hoc tests were used (α≤0.05).
Results: Findings showed that forced swimming training, methadone supplementation, and forced swimming training with methadone supplementation had no significant effect on AST (P=0.90) and ALT (P=0.99) enzymes; forced swimming training had significant effect on increase of ALP (P=0.001); also, forced swimming training, compared with methadone supplementation and combination of forced swimming training with methadone supplementation, had significant effect on increase of ALP (P=0.001).
Conclusion: Accordingly, 8 weeks of forced swimming training with methadone has possibly no significant effect on liver enzymes.
Hossein Berenjeian Tabrizi, Shadmehr Mirdar, Mohhamad Mahdi Moghanibashi, Zarbakht Ansari Pirsaraei,
Volume 6, Issue 4 (12-2016)
Abstract
Background & Objectives: It is well established that High-intensity Interval Training (HIT) may represent a time-efficient strategy to induce adaptations normally associated with endurance training. However, the effect of exercise on lung mitochondrial changes is not well understood.The purpose of the present study is to determine the effects of HIT on NRF-1 and PGC-1α genes at mRNA level in rat lung tissue.
Materials & Methods: Twenty Wistar male rats (4 weeks old, 68±9 g weight) were randomly assigned to 6-week training, 9-week training, 6-week control and 9-week control groups. High-intensity interval training program was started with 25 m/min and gradually reached to 70 m/min at the end of the ninth week. Following tissue sampling, RNA extraction and cDNA synthesis, and the expressions of genes were determined by real time RT-PCR technique.
Results: NRF-1 and PGC-1α genes expression were increased following interval training. The expression of NRF-1 and PGC-1α between 9-week training and 9-week control groups was significantly different (P≤0.05).
Conclusion: According to the current study, it seems that intense interval training can cause changes in the mitochondrial content and the possibly of mitochondrial biogenesis in lung tissue.
Bahareh Ketabdar, Mehrdad Fathie, ,
Volume 7, Issue 1 (5-2017)
Abstract
Background & Objective: The aim of the present study was to determine the effect of four-week high-intensity interval training with beta-alanine supplementation on aerobic and anaerobic performance and some blood parameters in girls basketball players.
Materials & Methods: This was a quasi-experimental study. Twenty female basketball players, with the mean age of 24.65 ± 4.81 years, height of 166.97 ± 4.12 cm, weight of 59.15 ± 5.23 kg and body mass index of 21.5 ± 1.23 kg/m2, were divided into two groups, including intervention (exercise + supplement) and control groups. Two days before and after the intervention, the subjects performed Wingate test (to estimate the average aerobic power) and Bruce test (to estimate VO2max).The subjects attended basketball training two sessions per week; Intervention group performed high-intensity interval training in addition to the basketball training in every session. The dose of beta-alanine supplementation was 2.4, 3.6, 4.8 g per day. After four weeks, creatine kinase and lactate levels and performance tests were reevaluated. Data were analyzed by SPSS software version 21, with a significance level of P<0.05.
Results: VO2max and anaerobic power increased significantly and fatigue index decreased significantly compared to the control group (p<0.05). But changes in the creatine kinase enzyme and lactate levels were not significant (p>0.05).
Conclusion: This study showed that high-intensity interval training with beta-alanine supplementation resulted in delay in the fatigue threshold, stabilization of PH and hydrogen ions balance, increased aerobic-anaerobic capacity and exercise performance in female basketball players.
Sharif Rezaei, Hassan Matinhomaee, Mohammad Ali Azarbayjani, Parvin Farzanegi,
Volume 7, Issue 1 (5-2017)
Abstract
Background & Objectives: C-kit+ cells are the most important cardiac stem cells and have Myogenic and Vasculogenic properties. Exercise training tends to stimulate these cells. This study aims to investigate the effect of intense and moderate interval aerobic training and curcumin consumption on the gene expression of c-Kit stem cells of heart in old rats.
Materials &Methods: 35 Wistar old female rats of about two years were randomly divided into 5 groups: control, saline, curcumin, moderate training + curcumin and intense training + curcumin. 30 mg Curcumin for each kg of their body weight was given by gavage to the rats in experimental groups 3 days a week. The saline group was given the same amount of saline. Both groups underwent interval aerobic training on treadmill 3 sessions per week for 8 weeks, with high and medium intensity. 48 hours after the last training and gavage, c-Kit gene expression for cardiac stem cells was measured.
Results: The results indicated that in each Curcumin group, c-Kit level increased significantly compared to that of the control group (P=0.003). The mean of moderate exercise + curcumin group was significantly higher than the mean of curcumin, saline and control groups (P<0.001). The highest increase in the level of c-Kit gene expression occurred in the intense training + curcumin group which showed a significant difference with other groups (P<0.001).
Conclusion: Regular consumption of curcumin alone or combined with regular aerobic interval exercise training can significantly increase the cardiac stem cells and can be effective in restoring old rats heart. The effect of exercise on the cardiac stem cells, however, appears to be dependent on the intensity of training.
Neda Abadi, Jabbar Bashiri,
Volume 7, Issue 2 (9-2017)
Abstract
Background & Objectives: Apoptosis in skeletal muscle plays an important role in disease-related tissue dysfunction such as muscle atrophy. Current evidence suggests that exercise training may alter apoptosis-related signaling and enzymes in skeletal muscle. Therefore, the purpose of this study was to investigate the effect of three-month aerobic training on AIF and caspase-9 gene expression in male rat soleus muscle.
Materials & Methods: This study was conducted as a two-group experimental design and sixteen 3-month-old male rats were selected and randomly divided into two groups of aerobic training (n=8) and control (n=8). Rats in trained group participated in the aerobic training program for three months (75-80%
). 48 hours after the last training session, the soleus muscle of rats were extracted and AIF and caspase-9 mRNA were evaluated by Real Time-PCR. Independent-samples t-test was applied to analyze the data (P<0.05).
Results: AIF gene expression of trained group was significantly higher than that of the control group (137.60%, P=0.01). Furthermore, caspase-9 gene expression of trained group was significantly higher than that of the control group (48.22%, P=0.01).
Conclusion: In general, it seems that a three-month aerobic training was effective in increasing soleus muscle mitochondrial apoptotic protein. However, more research needs to be done to identify the effects of exercise trainings on indices of apoptosis and skeletal muscle atrophy.
Amin Allah Dashtiyan, Mohammad Esmaeil Afzalpour, Nader Tanideh, Masood Sepehrimanesh,
Volume 7, Issue 3 (11-2017)
Abstract
Background & Objective: Physical activity and diet are the most important modifiable determinants of cancer risk. The aim of this study was to investigate the comparison of the effect of vitamin E on the expression of p53/PTEN prostate gland of male rats in two groups of intensive continuous and intermittent exercise training.
Materials & Methods: For this purpose, 56 male rats were randomly divided into 7 groups: [1] control group, [2] sham group, [3] intensive continuous training, [4] intensive intermittent training, [5] intensive continuous training + vitamin E, [6] intensive intermittent training + vitamin E, [7] vitamin E. The research training protocols were conducted in compliance with the principle of overload on the treadmill for six days a week, lasting 6 weeks. To measure expression changes of p53 and PTEN genes in rats' prostate, real-time PCR method was used and HPLC method was used to measure vitamin E. The One-way analysis of Variance test was used for comparisons among groups.
Results: Vitamin E in combination with continuous training induced a significant decrease in the p53 gene expression of IIT + VE group (p > 0/004) compared to the control group. In contrast, vitamin E in combination with intermittent training induced a significant decrease in expression of p53 (p>0/013) and a significant increase in the PTEN gene expression (p>0/035).
Conclusion: The results showed that physical exercise training reduced PTEN and p53 tumor suppressing gene expression by reducing oxidative stress, and vitamin E can be a somewhat increased expression of these genes.
Elham Ehrampoush, Seyed Amin Kouhpayeh, Mojtaba Farjam, Reza Homayounfar, Alireza Ghaemi,
Volume 7, Issue 4 (12-2017)
Abstract
Background & Objective: The duty of physicians in the new world is to promote health, prevent diseases and deliver primary health care. But in accordance with the Edinburgh Declaration, physicians are not trained to deal with these issues. One of the key areas that has an important role in the health of the population, contains the issues related to life style and particularly nutritional issues. Proper nutrition plays a major role in achieving optimal health outcomes and inpatient health care costs will be reduced. This article describes the experience of the implementation and results of the evaluation of providing a course of clinical nutrition for medical students.
Material & Methods: This action research study was conducted using census method, in collaboration with 50 students of Fasa University of Medical Sciences in the academic year 96-1395. In this study, clinical nutrition course was presented along with clinical courses for students. The data were gathered through pretest and posttest questionnaire, in each training session, and EDC questionnaire was applied to evaluate students' satisfaction. Descriptive statistics were used to analyze the results of the questionnaires.
Results: The comparison of students' score after each training session with pre-test scores, showed a significant increase in students' knowledge of clinical nutrition. Most students' satisfaction was related to the presentation (4.37) and the use of resources (4.32), respectively.
Conclusion: The results of this study demonstrated a positive effect of teaching clinical nutrition which can be considered by policymakers to insert this topic in the clinical course for medical students.
Soodabeh Chekachak, Mahdieh Molanouri Shamsi, Sara Soudi,
Volume 8, Issue 1 (4-2018)
Abstract
Background & Objective: Cytokines are molecules that are related to immunologic responses. Considering the antioxidant and immunologic effects of selenium nanoparticles and aerobic exercise training, the aim of this study was to examine the effects of aerobic exercise training and supplementation with selenium nanoparticles on protein content of Interleukin-4, Interleukin-6 and tumor necrosis factor Alpha in spleen tissue in mice with breast cancer.
Material and Methods: 64 Balb/c mice were randomly divided into 8 groups including Control-Health, Control-Tumor, Training-Healthy, Training-Tumor, Selenium nanoparticles-Health, Selenium nanoparticles-Tumor, Selenium nanoparticles-Training-Health and Selenium nanoparticles–Training-Tumor. Animals in different groups passed 6 weeks aerobic interval training and supplementation with selenium nanoparticles before and after cancer induction. At the end of the sixth week, cytokines protein levels in spleen tissue were measured by ELISA method.
Results: Based on the current study results exercise training and selenium nanoparticles caused significant decrease in tumor volume (P<0.05). Also, results showed that cancer induced a significant decrease in cytokines levels in tumor tissue (P<0.05). But concurrent using selenium nanoparticles and aerobic interval training induced increase in tumor necrosis factor Alpha levels in spleen tissue (P<0.05).
Conclusion: It seems that aerobic exercise training and selenium nanoparticles supplementation could have an effective role in the activation of immune system and decreasing in tumor volume, with increasing in tumor necrosis factor Alpha as a T helper 1 cytokine.
Maasomeh Shaki, Naser Baay, Ahmad Mazraeh,
Volume 8, Issue 1 (4-2018)
Abstract
Asiye Seyed, Sirous Farsi, Seyed Ali Hosseini, Gholamreza Kaka,
Volume 8, Issue 3 (12-2018)
Abstract
Background & Objective: Alcohol overdose can induce increment in free radicals. The present study aimed to investigate the effect of swimming training and Curcumin in withdrawal period of alcohol overdose on superoxide dismutase (SOD), glutathione peroxidase (GPX), total antioxidant capacity (TAC), malone dealdeid (MDA) and protein carbonyl (PC) of rats.
Materials & Methods: 40 rats were selected and administered alcohol every 8 hours for 4 days. Then they were subjected to the withdrawal of alcohol for six days and in seventh day divided in 5 groups of 8 rats (1) control (2) Curcumin (3) swimming training (4) Curcumin and swimming training (5) sham. Groups 3 and 4 swam 5 sessions per week for 2 weeks and groups 2 and 4 used Curcumin 5 times per week for 2 weeks peritoneally. For statistical analysis of data two-way ANOVA was used (p≤0.05).
Results: Swimming training had significant effect on increase of SOD (p=0.001), GPX (p=0.001) and TAC (p=0.009) and reduction of MDA (p=0.001) and PC (p=0.001) of rats. Curcumin had significant effect on increase of SOD (p=0.001) and GPX (p=0.001) and reduction of MDA (p=0.001) and PC (p=0.001) of rats but had no significant effect on TAC (p=0.34) also Curcumin and swimming training had interactive effects on increase of SOD (p=0.001) and GPX (p=0.001) and reduction of PC (p=0.009) of rats but had no interactional effect on TAC (p=0.48) and MDA (p=0.13).
Conclusion: Probably, swimming training and curcumin can be applied simultaneously in withdrawal period of alcohol overdose to increase antioxidant factors.
Hamid Reza Sadeghipour, Mohsen Salesi, Alireza Rabiezade ,
Volume 8, Issue 4 (12-2018)
Abstract
Background & Objective: Angiopoietin-like Proteins 8 (ANGPTL8) which secreted form adipose tissue due to downstream PGC-1α pathways, is the main factor for regeneration of beta cell. The aim of this study was to investigate the effect of 4 endurance training program on PGC-1α expression in adipose tissue, ANGPTL8 serum concentration and beta cell function (HOMA.B) in diabetic rats.
Materials & methods: Male Wistar rats (N=24) divided in 3 groups include healthy control (HC), diabetic control (DC) and endurance training (ET). After induction of diabetes with STZ, training groups performed 4 weeks endurance training and real-time polymerase chain reaction (Real-Time PCR) method used for the relative expression of PGC-1α in visceral adipose tissue, the enzyme-linked immunosorbent assay (ELISA) method for measuring serum ANGPTL8 levels. Also beta cell number was counted with pancreases hematoxylin-eosin evaluation. Results analyzed with ANOVA.
Results: The relative expression of mRNA PGC-1α was significantly increased in ET (P=0.001). Although ANGPTL8 levels increased in ET group, this change wasn’t significant (P=0.47). HOMA.B didn’t showed any significant change in ET (P=.0.08) but the number of beta cells in this group significantly increased (P=0.001). There was a positive correlation between relative mRNA PGC-1α and ANGPTL8 levels.
Conclusion: Despite the positive and significant correlation between relative expression of mRNA PGC-1α and ANGPTL8, this increase wasn’t significant, but this could increases the number of beta cell in endurance training group. Further studies with differences training programs are recommended.
Rezvan Kheirandish, Rouhollah Ranjbar, Ali Veisi,
Volume 8, Issue 4 (12-2018)
Abstract
Background & Objective: Irisin is myokine, that is secreted by acute exercise activity from the muscle and increases energy consumption. The purpose of this study was to determine the response of irisin serum and insulin resistance to acute pilates training sessions pilates training in obese sedentary women.
Materials & Methods: This research is a semi experimental study with pre-and post-test design. The statistical population of this study was made up of disabled obese women in Ahwaz, with 21 subjects (mean age 39.1±10.0 years and BMI 35.9±3.4 kg/m2) were randomly divided into Pilates group (n=12) and control group (n=9). The training group performed 60-minute Pilates training with a14-16 Borg perceived perception index, while the control group did not exercise. After at least 8 hours-fasting, blood samples were collected before and immediately after each activity, to measure the levels of Irisin, glucose, insulin and insulin resistance. Data were analyzed with paired-sample t-test and ANCOVA and the relationship between the variables was calculated by Pearson correlation test.
Results: The results indicated no significant changes in blood glucose, insulin, insulin resistance index and serum Irisin levels in Pilate’s group compared with the control group after a Pilates exercise session (p≥0.05). Furthermore, correlation was not between Irisin to, glucose, insulin, and insulin resistance index (p≥0.05).
Conclusion: Although research on this regard is a beginning pathway. However, Acute Pilates exercise does not seem to have an effect on glucose, insulin, insulin resistance, and Irisin level.
Fazlollah Fathollahi, Mohammad Faramarzi, Rouhollah Hemmati,
Volume 8, Issue 4 (12-2018)
Abstract
Background & Objective: Prostate cancer is the most common malignancy and the eighth cause of death in Iran. Angiogenesis is the major cause of metastatic and drug resistance in this cancer. The aim of this study was to investigate the effects of 10 weeks of high intensity periodic exercises on resting levels of some angiogenesis markers and also the pulmonary function of men with prostate cancer.
Materials & Methoed: 20 male patients with prostate cancer aged 55 to 62 years old were randomly divided into two groups (n = 10) and experimental (n = 10). The experimental group subjected to 10 weeks of periodic exercise with intensity progressed weekly, three sessions for 40 minutes and intensity of 70-75 was set for each session. 48 hours before and after exercise, the serum levels of VEGF, FGF, nitric oxide (NO) and also pulmonary function were measured. Intra and intergroup changes were analyzed using dependent t-test and independent t-test, respectively.
Results: The results showed that 10 weeks of severe periodic training significantly increased the levels of VEGF (P = 0.001), FGF (P = 0.001) and NO (P = 0.001) in the experimental group compared with the control group. Moreover, considering the results, FVC in patients with periodic exercise has increased significantly (P = 0.002).
Conclusion: As for results, it can be concluded that 10 weeks of periodic exercise increases the angiogenesis and pulmonary function in patients suffered from prostate cancer.
Leila Vesali-Akbarpoor, Mohammad Ali Samavati Sharif, Sima Mirzayi, Parivash Piraki,
Volume 8, Issue 4 (12-2018)
Abstract
Background & Objectives: Liver X-Alpha Receiver is a family of large hormone receptors that play a role in cholesterol homeostasis. The purpose of the present study was to investigate the effect of ten weeks of moderate and long term endurance exercise on the expression of the LXRα gene and the evaluation of serum levels of cholesterol and triglyceride in male rats.
Materials & Methods: 18 male Wistar rats were randomly divided in to three groups of six, control, moderate and long swimming, in the range of 275±25g. The training groups swam in 32 degrees water for ten weeks and 5 days a week. The moderate group swam for one hour and a long group each session for three hours. After the completion of the exercise, blood sampling from the underlying vena-cava and tissue from the rat liver was performed. Real-time PCR was used to measure the of LXRα gene expression by Ampliqon mixer and DNA synthesis kits. Differences were determined by ANOVA One-Way method and the groups were compared by Tukey follow-up test. Pearson correlation was used to determine the correlation between levels of expression of LXRα gene with cholesterol and triglyceride. SPSS software version20 was used at the significance level of p≤0.05.
Results: The moderate exercise group showed a significant increase in LXRα gene and a significant reduction in cholesterol and triglyceride compared to both control and prolonged groups (p=0.001). Also, LXRα gene expression in this group had a negative and significant correlation with cholesterol (rs=-0.912) and triglyceride (rs=-0.862).
Conclusion: It seems that the positive mechanism induced by moderate swelling by increasing the expression of the LXRα gene results in the release of cell lipid makers.
