Showing 8 results for nejati
Vahid Nejati, Khodabakhsh Ahmadi, Maryam Sharifian, Fatemah Shoaee,
Volume 1, Issue 4 (12-2011)
Abstract
Background & Objective: Quality of life in different age groups can consider as good predictor of elderly quality of life. The purpose of present study is comparing quality of life in different age decade.
Materials & Methods: This cross sectional study performed in 1914 citizens of Tehran with SF36 questionnaire. Sample selection method was multistage classification. We used One Way ANOVA for analysis.
Results: Findings show that quality of life dimension reduced in role physical, physical activity, general health, mental health and bodily pain. (P- Value was less than 0.05 for role physical and less than 0.01 for all others). Falling in bodily pain started in 30 years old and for general health 40, physical activity and mental health 60 and role physical role 70 years old.
Conclusion: Based on our finding education and intervention for bodily pain should be started at age 30 years old and for general health in 40 years old. Age matched physical activity should be educated for people above 60 years old.
Hajar Bahrami, Vahid Nejati, Hamidreza Pouretemad,
Volume 2, Issue 2 (8-2012)
Abstract
Background & Objective: Stuttering is a prevalent disorder in children and adolescents. Because attention is the only fuel resource for cognitive functions and the language have high cognitive functions, then it is possible that speech difficulties are related to attention deficit. The purpose of this study was to investigate the attentional demand of speech in children and adolescents with developmental stuttering.
Materials & Methods: It is a dependent measurement study though which 30 school students (8-13 yr.) were selected by convenience sampling and speech therapist´s detection from Shahriyar. The instruments were used in this research consist of: a text for reading, a device for recording of speech, and stuttering severity instrument-3 (SSI-3). The research was implemented in two conditions: single task (only reading) and dual task (reading along finger tapping task). The data were analyzed using T- test.
Results: Findings show that stuttering severity increased in dual task condition (divided attention).
Conclusion: This result suggests that a decreased attentional capacity in children with developmental stuttering cause an increase in the number of stuttering words. With a better understanding of attentional functions of stuttering people as an important cognitive variables, we can take a step toward recognizing cognitive vulnerability of disorder. Therefore, intervention programs for children with developmental stuttering should pay attention to cognitive deficits and prior to speech interventions, the cognitive deficits should be eliminated with neuropsychological implements. With the improvement of neurological base of speech which is the first point of that in the brain, the considerable improvement may be seen in the stuttering severity.
Hossein Ashraf , Reza Heydari, Vahid Nejati, Minoo Ilkhanipoor,
Volume 2, Issue 3 (11-2012)
Abstract
Background and Objective: Use of medicinal plants for attenuation of hyperglycemia and restoration of lipids to normal level is clinically very important. We decided to assess the preventive role of aqueous extract of Berberis Integerrima root on the serum levels of glucose, insulin, and lipid profile in Streptozotocin (STZ)-induced diabetic rats.
Materials and Methods: Forty male rats were divided into 5 groups as follows: 1- normal (N) 2- normal + barberry (N+B) (they received barberry root extract for 6 weeks) 3- diabetic (D) (they received STZ, 65 mg/kg BW /i.p.) 4- diabetic + barberry before (D+Bb) (they received barberry root extract for 3 weeks before STZ injection and continued for another three weeks) and 5- diabetic + barberry after (D+Ba) (three days after STZ injection, they received barberry root extract for 3 weeks). The experimental groups received barberry root extract (500 mg/kg bw) intra gastric by gavage for 6 weeks and the experimental period for each rat was 6 weeks.
Results: Diabetic rats showed a significant increase in serum glucose, total cholesterol, triglycerides, LDL-C, and food intake as well as a decrease in HDL-C, body weight and serum insulin, compared to the other groups. Administration of the barberry root extract in diabetic rats restored these changes towards normal to some extent.
Conclusion: In this study, for the first time, we showed that the administration of the barberry root extract before diabetes induction resulted in better amelioration in the serum levels of glucose, insulin, and lipid profile, compared to the group receiving it after induction: this indicates that the barberry root extract can play both a preventive and a therapeutic role in such patients.
Elham Ahmadi, Vahid Nejati, Gholamreza Najafi, Shiva Khezri,
Volume 5, Issue 1 (4-2015)
Abstract
Background & Objective: Epilepsy is one of the common neurological diseases and carbamazepine is an antiepileptic drug that causes oxidative stress, endocrine and the reproductive system long term disorders. The aim of this study is to evaluate the effect of wheat germ oil, as a rich source of antioxidants on sex hormones and uterine tissue in epileptic mice treated with carbamazepine.
Materials & Methods: In this study 48 adult female mice were randomly divided into 6 groups (n=8). Including: 1- control. 2- received pentylenetetrazol at dose of 40 (seizure control). 3- received pentylenetetrazol + carbamazepine at dose of 30. 4- received pentylenetetrazol + carbamazepine at dose of 180. 5- received pentylenetetrazol + carbamazepineat dose of 30 + wheat germ oil receiver at dose of 500. 6- received pentylenetetrazol + carbamazepine at dose of 180 + wheat germ oil at dose of 500.(units of doses are as grams/kilogram of body weight). At the end of the treatment period, ELISA method was used to measure estrogen, progesterone and testosterone levels . In addition, histological studies were performed on the uterus. Data were analyzed using ANOVA and Tukey's test in SPSS20 software.
Results: Carbamazepine levels of estrogen, progesterone, testosterone, and except of myometrium, the uterine thickness and average uterine glands decreased significantly. In the group with wheat germ oil + carbamazepine (30, 180), levels of mentioned factors changed near-normal significantly.
Conclusion: Results showed that the wheat germ oil improves reproductive system performance and reduces the complication of carbamazepine.
Faranak Nejati, Shiva Khezri, Homeira Hatami, Ali Reza Ali Hemmati,
Volume 5, Issue 2 (8-2015)
Abstract
Background & Objectives: Demyelination by Ethidium bromide is one of the ways that is usually used for preparing experimental models of MS. Treatment with estrogen protects oligodendrocyts from cell poisoning and stops lipidic peroxidation. The aim of this study is the evaluation of the effects of estrogen on anxiety like behavior and stress oxidative parameters after inducing demyelination by ethidium bromide to the cortex of cerebellum in rats.
Materials & Methods: Induction of demyelination was carried out in cerebellum cortex by direct injection of Ethidium Bromide (EB) (0.01%). One week after injection of EB, animals were treated with two doses of estrogen (2µg/μl and 4µg/μl) for 3 days. After the treatment stage, characteristics of anxiety were assessed by using Elevated plus Maze moreover , the parameters of stress oxidative were evaluated. One-way Analysis of Variance (ANOVA) was performed.
Results: The results of this study showed that Open Arm Entry percentage and open arm time (anxiety index) in rats with estrogen treatment was significant relative to Ethidium Bromide group (p<0.01) in addition , activity value of glutathione peroxidase and catalase showed significant increase compared to Ethidium Bromide group.
Conclusion: Microinjection of estrogen can decrease anxiety as well as oxidative stress.
Mohammadjavad Hosseinpoor, Hamid Parvin, Samad Nejatian, Vahideh Rezaee, Karamollah Bagherifard,
Volume 10, Issue 1 (4-2020)
Abstract
Background & Objective: Nowadays, in medical sciences, the amount of data on symptoms of people affected with various illnesses on one hand, and finding assistive techniques for the diagnosis of those diseases on the other, has been widespread. Consequently, the analysis and consideration of all factors involved in a disease are often challenging. Thus, a mechanized system to help discover the rules, identify patterns, and predict future events is absolutely needed. In this research, we intend to use a multi-objective algorithm to provide a method capable of detecting, extract sequences of variable-length from the genome, and count the interactions among them. In fact, these regulatory elements could play a significant role in the incidence and exacerbation of cancer.
Material & Methods: In this research, a proposed method for the detection of regulatory elements in the genome of a breast cancer patient has been used. The proposed method is implemented in MATLAB software. Also, to measure the performance and effectiveness of the suggested method, the proposed algorithm is implemented on HiC dataset, regarding patients with breast cancer in two blood cells GM12878 and CD34+ introduced by Mifsud et al.
Results: The results of implementing the proposed method are compared with the HiCUP method. The results show that the MSARE method has a better performance in detecting regulatory elements compared to the HiCUP method.
Conclusion: Experimental studies have shown that the two promoters BLC6 and HOTTIP discovered by the proposed method have had a significant effect on the incidence and severity of breast cancer in both blood cells GM12878 and CD34+.
Roghayeh Nejati, Ameneh Nematollahi, Mahsa Hasanzadeh, Ali Khani Jeihooni, Mehran Sayadi,
Volume 10, Issue 1 (4-2020)
Abstract
Background & Objective: Today in the world, environmental pollution due to heavy metals, their accumulation in the food chain and their dietary exposure are considered as a serious danger. The purpose of this study was to measure the amount of nickel, arsenic, lead, zinc and cadmium in liver, thigh, breast and gizzard parts of chicken distributed in Shiraz.
Materials & Methods: In this cross-sectional study, ten different brands of liver, thigh, breast and gizzard of chicken in Shiraz were collected from local markets and transferred to the laboratory with the cooling system. The concentration of heavy metals was measured by inductively coupled plasma atomic emission spectroscopy (ICP-OES).
Results: The mean concentrations of arsenic, cadmium, nickel, lead and zinc in liver tissues were 0.017, 0.061, 0.031, 0.057 and 15.15 µg/kg, in thigh muscles 5, 6, 28, 46 and 3310 µg/kg, in the breast muscles were 6, 8, 180, 50 and 4510 µg/kg and in the gizzard were 7, 29, 9, 19 and 12810 µg/kg, respectively. Heavy metals concentration was higher in liver tissue than other tissues.
Conclusion: The results indicated that the amount of heavy metals studied in chicken tissues are lower than world regulation standards. Also the results of risk assessment indicated that non-carcinogenic risk of these heavy metals due to chicken consumption is negligible while, the risk of carcinogenicity in the case of arsenic is higher compared to lead (relatively potential risk).
Mehran Sayadi, Mohammad Kiani, Ameneh Nematollahi, Roghayeh Nejati, Hashymihe Kabbidoraghi,
Volume 10, Issue 4 (11-2020)
Abstract
Nowadays, food safety and security is one of the main issues of human life concerns. Parallel to this, food health also becomes significant for agricultural product consumers. Although organophosphate pesticides such as malathion can have adverse effects on consumer health, they are widely used in food production to increase food security. Results show that besides pesticides benefits, there are some problems such as reduced biodiversity, reduced nitrogen fixation and destruction of fauna residential place specially birds and endangered species. Some of the used pesticides have side effects such as increased salivation, nasal and eye discharge, bronchoconstriction, meiosis, gastrointestinal cramps, high blood pressure and various genetic disorders are left on human bodies. Due to the residues of these toxins in food products, there are many concerns for the health of consumers that use various methods such as washing, peeling and fermentation which can greatly reduce the residual pesticides in food. Although systemic toxins and penetrating toxins from fruits and vegetables do not last for a period of time after their use, they remain in agricultural products and fruits that are not removed by washing, heating, and freezing. Therefore, it is recommended that you use chemical pesticides as a last resort.
