en مروری بر علائم گوارشی COVID-19 ، عوارض و پروتکل های درمانی موجود گوارش Gastroenterology مروری Review <div style="text-align: justify;"><strong><em>Background & Objective</em></strong><em>:</em> Corona virus disease 2019 (COVID-19) is an emerging outbreak which has involved almost all of the countries of the world now. While the main symptoms of the disease are known to be respiratory symptoms like coughing and shortness of breath, extrapulmonary symptoms have also been reported in many cases of COVID-19. Gastrointestinal (GI) manifestations including diarrhea, nausea and vomiting, abdominal pain and liver injury are amongst the most common extrapulmonary symptoms in COVID-19 patients.<br> <strong><em>Materials & Method</em></strong><em>:</em> We used Scopus, PubMed, and Google scholar databases for this review. The last search was run on November 21, 2020<br> <strong><em>Results:</em></strong> Liver injury is mostly accompanied by an elevation in AST and ALT levels and a slight increase in serum billirubin levels that is observed in approximately 14.8-53.1% of COVID-19 patients.1-29% of COVID-19 patients present nausea and vomiting and 2 to 10% develop diarrhea. Abdominal pain is seen in about 2.2-6% of COVID-19 patients and most frequently seen in severely ill patients.<br> <strong><em>Conclusion:</em></strong> Diarrhea, nausea, and vomiting and liver injury are the most common GI symptoms in COVID-19 patients while abdominal pain is not pretty common. There are no medications of proven efficacy to treat COVID-19 or its GI manifestations so far.<br> &nbsp;</div> <br> <gdiv></gdiv> COVID-19, gastrointestinal manifestations, treatment protocols, extra pulmonary 3895 3902 http://jabs.fums.ac.ir/browse.php?a_code=A-10-1205-3&slc_lang=en&sid=1 Fatemeh Heiat فاطمه هیئت auf.heyat@yahoo.com 100319475328460026378 100319475328460026378 No Department of Physical Education and Sport Sciences, Fasa Branch, Islamic Azad University, Fasa, Iran گروه تربیت بدنی و علوم ورزشی، دانشگاه آزاد اسلامی واحد فسا، فسا، ایران Ramin Hosseinzadeh رامین حسین زاده 100319475328460026379 100319475328460026379 No Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران Mohammadali Abyazi محمدعلی ابیزی 100319475328460026380 100319475328460026380 No Baqiyatallah Research Center for Gastroenterology and Liver Diseases, Baqiyatallah University of Medical Sciences, Tehran, Iran مرکز تحقیقات گوارش و کبد بقیه الله، دانشگاه علوم پزشکی بقیه الله، تهرن، ایران Reza Ranjbar رضا رنجبر 100319475328460026381 100319475328460026381 No Molecular Biology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran مرکز تحقیقات زیست شناسی مولکولی، موسسه سم شناسی و زیست شناسی سیستم ها، دانشگاه علوم پزشکی بقیه الله، تهرن، ایران Ahmad Khonche احمد خنچه dr.khonche@yahoo.com 100319475328460026382 100319475328460026382 No Baqiyatallah Research Center for Gastroenterology and Liver Diseases, Baqiyatallah University of Medical Sciences, Tehran, Iran مرکز تحقیقات گوارش و کبد بقیه الله، دانشگاه علوم پزشکی بقیه الله، تهرن، ایران Mohammad Heiat محمد هیئت mohamad.heiat@gmail.com 100319475328460026383 100319475328460026383 Yes Baqiyatallah Research Center for Gastroenterology and Liver Diseases, Baqiyatallah University of Medical Sciences, Tehran, Iran مرکز تحقیقات گوارش و کبد بقیه الله، دانشگاه علوم پزشکی بقیه الله، تهرن، ایران